| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
A novel micelle formation was established using “irreversible” photoreactions as a driving force of molecular self-assembly. The photolysis, photorearrangement, coupled with photo salt formation served as a driving force of the self-assembly of diblock copolymers to produce nanosized micelles through a change in situ from the nonamphiphilic copolymers into the amphiphilic ones. The photopolymerization also induced the self-assembly of an amphiphilic diblock copolymer to provide microsized giant vesicles. The vesicles had some morphologies of spherical micelles, spherical vesicles, worm-like vesicles, and a bilayer sheet, depending on the composition of the monomer units. The giant vesicles had several similarities to biomembrane not only in their size and structure but also in the stimuli-responsive behavior and membrane permeability, suggesting that the vesicles consisting of the diblock copolymer could be a possible artificial model of the biomembrane.
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