Elucidation of formation mechanism of luminescent nanoparticles prepared by laser ablation in liquid and their application in biomedical engineering
| Project/Area Number |
25390014
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nanomaterials chemistry
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| Research Institution | Tokyo Institute of Technology |
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Principal Investigator |
Wada Hiroyuki 東京工業大学, 総合理工学研究科(研究院), 准教授 (00422527)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
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| Keywords | アップコンバージョン / 蛍光体 / ナノ粒子 / レーザー / がん治療 / レーザープロセッシング / 結晶性 / 蛍光 / 光線力学的療法 / 液中レーザーアブレーション |
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| Outline of Final Research Achievements |
Upconversion nanoparticles were prepared by laser ablation in liquid, which was irradiation with focused laser beam on material in water. Experiment using cancer cells indicated that they were useful for cancer therapy, which was photodynamic therapy (PDT). In the case of normal PDT, it is difficult to cure large or deep cancer. However, this study showed that PDT with using upconversion nanoparticles and near-infrared light, which is transparent for a living body, was likely to solve the problem.
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Report
(4 results)
Research Products
(62 results)
