Study on liquid-liquid transtion of protein hydaration water by collective dynamics and liquid strcuture analysis
| Project/Area Number |
25390130
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Quantum beam science
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| Research Institution | Fukuoka University |
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Principal Investigator |
Yoshida Koji 福岡大学, 理学部, 助教 (00309890)
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| Co-Investigator(Renkei-kenkyūsha) |
YAMAGUCHI TOSHIO 福岡大学, 理学部, 教授 (70158111)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2014: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | タンパク質 / 水和 / X線回折 / 中性子散乱 / X線散乱 / Ｘ線回折 |
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| Outline of Final Research Achievements |
Collective dynamics and structure of hydration water for hydrated proteins and polypeptides were investigated by neutron and X-ray scatterings in the temperature range of 298 - 180 K. Hydration structure of proteins and amino acids confined in mesoporous silica and nano-water domain formed in ionic liquid-water mixture. The relation between protein dynamics and water was clarified and the water role in protein function was discussed.
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Report
(4 results)
Research Products
(19 results)
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[Journal Article] Thermal behavior, structure, and dynamics of low-temperature water confined in mesoporous organosilica by differential scanning calorimetry, X-ray diffraction, and quasi-elastic neutron scattering2013
Author(s)
M. Aso, K. Ito, H. Sugino, K. Yoshida, T. Yamada, O. Yamamuro, S. Inagaki, T. Yamaguchi
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Journal Title
Pure Appl. Chem
Volume: 85
Issue: 1
Pages: 289-305
DOI
Related Report
Peer Reviewed
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