Application of knot theory to molecular biology
Project/Area Number |
25400080
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Geometry
|
Research Institution | Saitama University |
Principal Investigator |
SHMOKAWA Koya 埼玉大学, 理工学研究科, 教授 (60312633)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | 結び目 / DNA / 組換え / バンド手術 / 格子結び目 / 組換え酵素 / デーン手術 |
Outline of Final Research Achievements |
We studied band surgeries of knots and links, lattice knots in the simple cubic lattice, Dehn surgery on knots and A-polynomial of knots and applied results to modeling of DNA and proteins and the research of site-specific recombination. In particular we studied (1)characterization of unlinking of DNA catenane by site-specific recombination of Xer-dif-FtsK system, (2)tangle decomposition of knots and their A-polynomial, (3)lattice knots and links in a tube region in the simple cubic lattice. We published 4 research papers and give plenary and invited talks in international conferences. We also organized a special session on DNA topology in Australia.
|
Report
(4 results)
Research Products
(24 results)
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] Knots and links in the simple cubic lattice2015
Author(s)
Koya Shimokawa
Organizer
Simons Center's Workshop: Symplectic and Algebraic Geometry in the Statistical Physics of Polymers
Place of Presentation
Simons Center of Geometry and Physics, Stony Brook University, NY, USA
Year and Date
2015-10-13
Related Report
Int'l Joint Research / Invited
-
-
-
-
-
-
-
-
-
[Presentation] Lattice knots and links in tubes
Author(s)
下川 航也
Organizer
Entanglement in biology; how nature controls the topology of proteins and DNA
Place of Presentation
Banff International Research Station for Mathematical Innovation and Discovery, Canada
Related Report
Invited
-
-
-