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Stochastic analysis on models of population genetics

Research Project

Project/Area Number 25400143
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Basic analysis
Research InstitutionFukuoka Women's University (2016)
Kyushu Dental College (2013-2015)

Principal Investigator

IIZUKA MASARU  福岡女子大学, 国際文理学部, 学術研究員 (20202830)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords集団遺伝学 / 分子進化 / 確率モデル / 確率過程 / マルコフ過程 / 出生死滅過程 / 拡散過程 / 遺伝子重複 / 遺伝子変更 / モラン・モデル / ライト=フィッシャー・モデル / 拡散近似
Outline of Final Research Achievements

Various models of population genetics were studied by means of stochastic analysis. First, the properties and the relation of two stochastic models (Wright-Fisher model and Moran model) in random environments due to stochastic selection were revealed. Next, some properties of the multi-dimensional models of compensatory fitness interaction with indirect compensation or gene duplication were formulated and their properties on the first hitting time to some boundary point were studied. Further, some limit theorems were obtained for the strong selection and weak mutation limit of Moran model.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (9 results)

All 2016 2015 2014 Other

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (6 results) (of which Invited: 4 results)

  • [Journal Article] A model of compensatory molecular evolution involving multiple sites in RNA molecules2016

    • Author(s)
      Junko Kusumi, Motoshi Ichinose, Masasuke Takefu, Robert Piskol, Wolfgang Stephan and Masaru Iizuka
    • Journal Title

      Journal of Theoretical Biology

      Volume: 388 Pages: 96-107

    • DOI

      10.1016/j.jtbi.2015.10.008

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] The weak mutation and strong selection limit of the Moran model satisfies the strong Markov property2015

    • Author(s)
      T. Takemura, M. Tomisaki and M. Iizuka
    • Journal Title

      Ann. Reports of Graduate School of Humanities and Sciences, Nara Women ’s University

      Volume: 30

    • NAID

      120006657952

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] On the convergence of weak mutation limits of the Moran model in population genetics2014

    • Author(s)
      T. Takemura, M. Tomisaki and M. Iizuka
    • Journal Title

      Ann. Reports of Graduate School of Humanities and Sciences, Nara Women ’s University

      Volume: 29

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 遺伝子変更が互助的相互作用による分子進化に及ぼす効果の数理的解析2016

    • Author(s)
      飯塚 勝
    • Organizer
      九州分子進化セミナー
    • Place of Presentation
      九州大学・伊都キャンパス
    • Year and Date
      2016-11-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] 遺伝子重複の効果を含む互助的相互作用による分子進化機構の確率モデルの定式化2016

    • Author(s)
      飯塚 勝
    • Organizer
      九州分子進化セミナー
    • Place of Presentation
      九州大学・伊都キャンパス
    • Year and Date
      2016-07-01
    • Related Report
      2016 Annual Research Report
  • [Presentation] Model of Compensatory Molecular Evolution with Direct and Indirect Compensation2014

    • Author(s)
      M. Iizuka
    • Organizer
      ミュンヘン大学バイオセンター (Biocenter, University of Munich) ・セミナー
    • Place of Presentation
      ミュンヘン大学(ドイツ・ミュンヘン市)
    • Year and Date
      2014-09-04
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 集団遺伝学に現れる確率モデルの弱突然変異極限

    • Author(s)
      飯塚勝
    • Organizer
      九州確率論セミナー
    • Place of Presentation
      九州大学・伊都キャンパス(福岡市)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Model of compensatory molecular evolution with indirect compensation

    • Author(s)
      M. Iizuka
    • Organizer
      ミュンヘン大学バイオセンター・セミナー
    • Place of Presentation
      ミュンヘン大学(ドイツ、ミュンヘン市)
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] A model of compensatory molecular evolution with indirect compensation

    • Author(s)
      J. Kusumi, M. Ichinose, M. Takefu, W. Wtephan, and M. Iizuka
    • Organizer
      SMBE Satellite Meeting/ NIG International Symposium ''The Causes of Genome Evolution"
    • Place of Presentation
      Toray Conference Center(三島市)
    • Related Report
      2013 Research-status Report
    • Invited

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Published: 2014-07-25   Modified: 2019-07-29  

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