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Properties of Hybrid Liposomes Investigated with Neutron Spin Echo

Research Project

Project/Area Number 25400433
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Biological physics/Chemical physics/Soft matter physics
Research InstitutionHigh Energy Accelerator Research Organization

Principal Investigator

Endo Hitoshi  大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 准教授 (40447313)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords中性子小角散乱 / リポソーム / 界面活性剤 / マイクロエマルジョン / 相転移 / 構造解析 / 小角散乱 / リン脂質 / リン脂質二重膜 / 中性子スピンエコー / 膜ダイナミクス / ハイブリッドリポソーム
Outline of Final Research Achievements

In this study, the structures of hybrid liposomes (HL) with lipid and non-ionic surfactant were investigated by small-angle neutron scattering, small-angle X-ray scattering, dynamic light scattering, and so on. As the results, the structures of HL are affected by the ratio of non-ionic surfactant as well as temperature. The effect of the temperature has been newly found by this research, which should be deeply studied further.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (14 results)

All 2015 2014 2013

All Journal Article (7 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Acknowledgement Compliant: 1 results,  Open Access: 1 results) Presentation (7 results) (of which Int'l Joint Research: 1 results,  Invited: 4 results)

  • [Journal Article] Spin Fluctuations from Hertz to Terahertz on a Triangular Lattice2015

    • Author(s)
      Yusuke Nambu, Jason S. Gardner, Douglas E. MacLaughlin, Chris Stock, Hitoshi Endo, Seth Jonas, Taku J. Sato, Satoru Nakatsuji, and Collin Broholm
    • Journal Title

      Phys. Rev. Lett.

      Volume: 115 Issue: 12

    • DOI

      10.1103/physrevlett.115.127202

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] 中性子準弾性散乱による高分子溶液ダイナミクスの研究2015

    • Author(s)
      遠藤 仁
    • Journal Title

      RADIOISOTOPES

      Volume: 64 Pages: 577-587

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Collective Structural Changes in Vermiculite Clay Suspensions Induced by Cesium Ions2014

    • Author(s)
      Ryuhei Motokawa, Hitoshi Endo, Shingo Yokoyama, Shotaro Nishitsuji, Tohru Kobayashi, Shinichi Suzuki, Tsuyoshi Yaita
    • Journal Title

      SCIENTIFIC REPORTS

      Volume: 4 Issue: 1

    • DOI

      10.1038/srep06585

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Mesoscopic Structures of Vermiculite and Weathered Biotite Clays in Suspension with and without Cesium Ions2014

    • Author(s)
      Ryuhei Motokawa, Hitoshi Endo, Shingo Yokoyama, Hiroki Ogawa, Tohru Kobayashi, Shinichi Suzuki, Tsuyoshi Yaita
    • Journal Title

      Langmuir

      Volume: 30 Issue: 50 Pages: 15127-15134

    • DOI

      10.1021/la503992p

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] 中性子を利用したナノ構造解析2014

    • Author(s)
      瀬戸秀紀、遠藤仁、鳥飼直也
    • Journal Title

      科学と工業

      Volume: 88 Pages: 96-96

    • NAID

      40020013487

    • Related Report
      2014 Research-status Report
  • [Journal Article] 中性子スピンエコー測定で何が分かるのか?2014

    • Author(s)
      遠藤仁
    • Journal Title

      中性子科学会誌「波紋」

      Volume: 24 Pages: 206-209

    • NAID

      130007510561

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Dynamics of Polystyrene in a Theta Solvent Investigated by Neutron Spin Echo2013

    • Author(s)
      Hitoshi Endo
    • Journal Title

      Journal of Physical Society Japan

      Volume: 82 Suppl. A

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Mesoscopic structure of nanogels studied by small-angle neutron scat-tering and computer simulation2015

    • Author(s)
      Hitoshi Endo
    • Organizer
      JCNS Workshop 2015 Neutron Scattering on Nano-Structured Soft Matter: Synthetic- and Bio-Materials
    • Place of Presentation
      Tutting (Germany)
    • Year and Date
      2015-10-05
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 中性子小角散乱と計算機シミュレーションを組み合わせたナノゲルの構造解析2015

    • Author(s)
      遠藤 仁
    • Organizer
      第64回高分子討論会
    • Place of Presentation
      東北大学川内キャンパス(宮城県仙台市)
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] Neutron Resonance Spin Echo Spectrometers, VIN-ROSE, at J-PARC2014

    • Author(s)
      Hitoshi ENDO, Masahiro HINO, Norifumi YAMADA, Tatsuro ODA, Yuji KAWABATA, Hideki Seto
    • Organizer
      QENS 2014 / WINS 2014
    • Place of Presentation
      Autrans, France
    • Year and Date
      2014-05-11 – 2014-05-16
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Structure and Dynamics of Protein in Solution Investigated by Neutron Scattering2014

    • Author(s)
      Hitoshi Endo
    • Organizer
      13th Japan-Korea Meeting on Neutron Science
    • Place of Presentation
      Bueyo, Korea
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Neutron Resonance Spin Echo Spectrometers, VIN-ROSE, at J-PARC2014

    • Author(s)
      Hitoshi Endo
    • Organizer
      Joint Conference between 11th International Conference on Quasielastic Neutron Scattering 6th Workshop on Inelastic Neutron Spectrometers
    • Place of Presentation
      Autrans, France
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 中性子スピンエコー法を用いたタンパク質の水溶液中のダイナミクス研究2013

    • Author(s)
      遠藤仁
    • Organizer
      第62回高分子討論会
    • Place of Presentation
      金沢大学角間キャンパス
    • Related Report
      2013 Research-status Report
  • [Presentation] 中性子スピンエコーを用いたタンパク質溶液のダイナミクス評価2013

    • Author(s)
      遠藤仁
    • Organizer
      日本中性子科学会第13回年会
    • Place of Presentation
      ちば県民プラザ
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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