Mechanism of stacking of phospholipid nanodisks and trial for manufacturing layer-by-layer made of nanodisks

• Project/Area Number: 25400434
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Biological physics/Chemical physics/Soft matter physics
• Research Institution: High Energy Accelerator Research Organization
• Principal Investigator: YAMADA Norifumi 大学共同利用機関法人高エネルギー加速器研究機構, 物質構造科学研究所, 助教 (90425603)
• Project Period (FY): 2013-04-01 – 2017-03-31
• Project Status: Completed (Fiscal Year 2016)
• Budget Amount: ¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
• Keywords: 表面・界面物性 / 自己組織化 / 量子ビーム / ナノ材料

Outline of Final Research Achievements

In this proposal, studies for understanding mechanism of stacking of phospholipid nanodisks and trial for manufacturing layer-by-layer made of the nanodisks was performed.

Research Products

• [Presentation] X線/中性子小角散乱を用いたF-BARタンパク質による模倣生体膜の変形挙動の観察 (2016)
  • Author(s): 山田悟史, 川崎政人, 長尾道弘
  • Organizer: 日本物理学会2016年秋季大会
  • Place of Presentation: 金沢大学角間キャンパス(石川県金沢市)
  • Year and Date: 2016-09-13
• [Presentation] 秒オーダー時分割中性子反射率法によるリン脂質積層膜の水和過程のkinetics観測 (2015)
  • Author(s): 山田悟史
  • Organizer: 第62回高分子討論会
  • Place of Presentation: 金沢大学角間キャンパス（石川県・金沢市）
  • Year and Date: 2015-09-15
• [Presentation] Kinetics of unbinding transition induced by electrostatic interaction on hydration process of phospholipid multilayers on a substrate (2015)
  • Author(s): N. L. Yamada, M. Sferrazza, T. Hirata, K. Tanaka
  • Organizer: 6th European Conference on Neutron Scattering
  • Place of Presentation: ザラゴザ（スペイン）
  • Year and Date: 2015-09-02
  • Int'l Joint Research
• [Presentation] リン脂質二分子膜の水和過程における静電相互作用によるunbinding転移のkinetics (2014)
  • Author(s): 山田悟史
  • Organizer: 日本物理学会2014年秋季大会
  • Place of Presentation: 中部大学春日井キャンパス
  • Year and Date: 2014-09-07 – 2014-09-10
• [Presentation] 中性子反射率計SOFIAにおける時分割測定用試料環境の開発 (2014)
  • Author(s): 山田悟史
  • Organizer: 日本物理学会2014年秋季大会
  • Place of Presentation: 中部大学春日井キャンパス
  • Year and Date: 2014-09-07 – 2014-09-10
• [Presentation] Development of sample environments of SOFIA reflectometer for seconds-order time slicing measurement (2014)
  • Author(s): N. L. Yamada, K. Mitamura, H. Sagehashi, N. Torikai, S. Sato, H. Seto, M. Furusaka, T. Oda, M. Hino, T. Fujiwara, M. Kobayashi, and A. Takahara
  • Organizer: the 2nd International Symposium on Science at J-PARC
  • Place of Presentation: EPOCHAL TSUKUBA, Tsukuba, Japan
  • Year and Date: 2014-07-13 – 2014-07-15
• [Presentation] In-situ measurement of phospholipid-nanodisk adhesion on substrates by neutron reflectometry and atomic force microscopy (2014)
  • Author(s): N. L. Yamada, M. Sferrazza, and S. Fujinami
  • Organizer: the sixth Taiwan-Japan workshop on X-ray and neutron scattering
  • Place of Presentation: Howard Civil Service International House, Taipei, Taiwan
  • Invited
• [Presentation] Nanopore formation and reconstruction of small unilamellar vesicles consisting of long- and short-chain phospholipids (2013)
  • Author(s): N. L. Yamada
  • Organizer: 27th Conference of the European Colloid and Interface Society
  • Place of Presentation: Sofia Princess Hotel, Sofia, Bulgaria
• [Presentation] Nanopore formation and reconstruction of small unilamellar vesicles consisting of long- and short-chain phospholipids (2013)
  • Author(s): N. L. Yamada
  • Organizer: International Soft Matter Conference 2013
  • Place of Presentation: the University La Sapienza, Rome, Italy
• [Book] 材料表面の親水・親油の評価と制御設計 (2016)
  • Author(s): 石井淑夫 監修（執筆者 72名）
  • Total Pages: 600
  • Publisher: テクノシステム
• [Remarks] 山田 悟史氏、日本中性子科学会奨励賞、日野 正裕氏、技術賞を受賞
  • URL: http://www2.kek.jp/imss/news/2014/topics/1218JSNS-Awd/