| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Outline of Final Research Achievements |
In terahertz spectrum region, many low frequency intermolecular vibrational modes based on weak interaction such as hydrogen bonding and Vander Waals force can be observed. The purpose of this research is to develop circular dhicroism measurement system at THz region and then, to observe conformational dynamics of proteins. Besides, to seek possibility of conformation control of proteins by using intense coherent THz wave.
We successfully developed THz circular dhicroism system with form birefringence waveplate. Signal of circular dhicroism measurement at THz frequency region were not obtained with sufficient SN ratio in the experiment, however, spectrum difference in UV circular dhicroism and fluorescence measurements which imply conformational transition due to intense THz radiation can be observed.
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