Stereoselective synthesis of alkenes using new Julia-type reagents
| Project/Area Number |
25410111
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Synthetic chemistry
|
|---|
| Research Institution | Gifu University |
|---|
Principal Investigator |
Ando Kaori 岐阜大学, 工学部, 教授 (70211018)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
OKA NATSUHISA 岐阜大学, 工学部, 准教授 (50401229)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Keywords | シス‐オレフィン / Julia-Kocienski reaction / アルケン合成 / 立体選択的 / Julia形オレフィン化反応 / スルホンアニオン / メチレン化剤 / シス-1,3-ジエン / オレフィン化反応 / カルボニル化合物 / 立体選択性 / Julia型反応 / テトラゾイルスルホン / Julia-Kocienski反応 / 合成化学 |
|---|
| Outline of Final Research Achievements |
Although Julia-Kocienski reaction is a efficient tool for direct trans-alkene synthesis via metalated tetrazolylsulfones with aldehydes, cis-selective reagents are also needed. In this study, we developed a practical methylenation reation for aldehydes and ketones using new Julia-type reagents. Based on this results, we also found cis selective reaction for the synthesis of 1,3-dienes.
|
Report
(4 results)
Research Products
(27 results)
-
-
-
-
-
-
-
-
-
[Journal Article] Purification and comparison of native and recombinant tRNA-guanine transglycosylases from Methanosarcina acetivorans.2013
Author(s)
Nomura, Y, Onda, Y, Ohno, S, Taniguchi, H, Ando, K, Oka, N, Nishikawa, K, Yokogawa, T
-
Journal Title
Protein Expr. Purif.
Volume: 88
Issue: 1
Pages: 13-19
DOI
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
[Presentation] The synthetic mechanism of tRNA modificarions in thermophilic bacteria2013
Author(s)
Takuya Kawamura, Chie Tomikawa, Tahayuki Ohira, Yasushi Inoue, Nobukazu Nameki, Natsuhisa Oka, Hiroki Taniguchi, Kaori Ando, Satoshi Ohno, Akihiko Yamagishi, Tsutom Suzuki, Takashi Yokogawa, Hiroyuki Hori
Organizer
Riboclub 2013 Annual Meeting, Canada
Place of Presentation
Canada
Related Report
-
-
-
-
-
