Development of an Automated Synthesizer of Oligosaccharides Based on the Electrochemical Method
| Project/Area Number |
25410115
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Tottori University |
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Principal Investigator |
Nokami Toshiki 鳥取大学, 工学(系)研究科(研究院), 准教授 (60402963)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Keywords | 糖鎖 / 自動合成 / 有機化学 / 電解合成 / 電解酸化 / グリコシル化 / 天然物 |
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| Outline of Final Research Achievements |
To synthesize biologically active oligosaccharide efficiently, we have developed an automated synthesizer for oligosaccharide based on electrochemical method. Carbohydrate building blocks used in this study were stable, easy to handle, and easy to prepare. It is also easy to perform large-scale synthesis and analyze the reactions, because the method is based on solution-phase synthesis. We expect that the synthesizer can be a popular edition of an automated oligosaccharide synthesizer, which is available in reasonable price.
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Report
(4 results)
Research Products
(31 results)
