| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
We have developed three types of oxidation reactions, i.e., (1) synthesis of arylacetaldehydes via anti-Markovnikov Wacker-type oxidation, (2) synthesis of terminal acetals, (3) synthesis of benzaldehydes via oxidative cleavage of carbon-carbon double bond, using palladium catalysts and vinylarenes as substrates. These reactions proceeded under 1 atm of molecular oxygen (as a terminal oxidant) and mild reaction conditions, and thus these can be regarded as novel environmental load-reducing synthesis of aldehydes and their derivatives from terminal alkenes. The use of cyclic electron-deficient alkenes such as maleimide as additives was the key of the present reactions to enhance the catalytic activity.
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