| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
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| Outline of Final Research Achievements |
The main purpose of this research is to fabricate a novel molecular system, in which artificial polymers are conjugated with bio-related peptides as graft chains. An elastin-like peptide (ELP), which is known to take thermo-responsive conformational transition, has been employed as a peptide and attached to the pH-responsive poly(acrylic acid) and poly(allylamine) as graft chains. These conjugates have successfully shown LCST (lower critical solution temperature) behaviors responsive to dual stimuli of pH and temperature. The alternate layer-by-layer assembly prepared from such anionic and cationic conjugates has shown a reversible structural color variation based on thermo-induced polarity change of ELP chains.
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