Development of new analysis protocols for identification and imaging of molecules in tissues
| Project/Area Number |
25410143
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Analytical chemistry
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| Research Institution | Seikei University (2014-2016)
Shimane University (2013) |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2016: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 質量イメージング / 表面科学 / TOF-SIMS / 多変量解析 / 近接場赤外顕微鏡 / ToF-SIMS / データ解析 / イメージング / 国際情報交換 イギリス / 国際情報交換 ドイツ |
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| Outline of Final Research Achievements |
Time-of-flight secondary ion mass spectrometry (TOF-SIMS) is a powerful analysis method because it provides detailed chemical images with high spatial resolution approximately 100 nm. However, it is often difficult to interpret TOF-SIMS data, especially for the analysis of unknown materials in multicomponent samples, due to complex spectrum information. New analysis protocols for identification and imaging of molecules in complex samples using TOF-SIMS and near-field infrared microscopy, which also provides chemical mapping, have been developed.
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Report
(5 results)
Research Products
(20 results)
