| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
|
|---|
| Outline of Final Research Achievements |
This study focuses on the development of facile fabrication of gold nanoparticles (AuNPs) that can enable selective and high-sensitive colorimetric detection of toxic mercury Hg(II) ions. We prepared a peptide-substituted ligand (DGAA-A3) consisting of gold-binding peptide (A3) fused to diglycolamic acid framework (DGAA) with selectivity for Hg(II) ions. We have developed a simple one-pot strategy to fabricate DGAA-decorated AuNPs using the DGAA-A3 that can simultaneously direct both the synthesis of AuNPs and the immobilization of DGAA on the AuNPs in a single step. In addition, DGAA-decorated AuNPs can detect Hg(II) ions by simple color change from red to blue, based on cross-linkage of AuNPs by binding between Hg(II) ions and DGAA on the AuNPs.
|
