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Fluid-Structure Interaction Analysis for OSAS Mechanism

Research Project

Project/Area Number 25420136
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Fluid engineering
Research InstitutionGifu National College of Technology

Principal Investigator

YAMAMOTO Takahisa  岐阜工業高等専門学校, その他部局等, 准教授 (10345960)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords数値流体力学 / 閉塞型睡眠時無呼吸症候群 / 数値流体力学解析 / 生体模型
Outline of Final Research Achievements

Uvulopalatopharyngoplasty (UPPP) is one of radical treatment for Obstructive Sleep Apnea Syndrome (OSAS). However, the effectiveness of the treatment is just 50%. This study had analyzed UPPP and OSAS from engineering point of view. From the results, this study had made clear following characteristics of UPPP and OSAS; (1) UPPP makes morphological change in nasal-pharynx region drastically, and (2) correlation coefficient between treatment effectiveness of UPPP and dilatation of restricted area in pharynx is relatively low. These results indicate the reason why the effectiveness of UPPP is just 50%. From the results of numerical analysis threshold of wall shear stress is found in OSAS mechanism. Prediction of the wall shear stress is able to make clear the effectiveness of UPPP before the treatment.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (11 results)

All 2017 2016 2015 2014

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Acknowledgement Compliant: 1 results) Presentation (9 results) (of which Int'l Joint Research: 1 results,  Invited: 1 results)

  • [Journal Article] 好酸球性副鼻腔炎の術後再発に対する経鼻呼出療法: CFD解析を用いた鼻咽頭内エアロゾル輸送特性の検討2017

    • Author(s)
      山本高久,小林良樹,朝子幹二,友田幸一
    • Journal Title

      日本耳鼻咽喉科感染症・エアロゾル学会論文集

      Volume: 1 Pages: 1-6

    • NAID

      130007884546

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Volumes of Velopharyngeal and Glossopharyngeal Airway Were Not Changed after Uvulopalatopharyngoplasty: Report of Three Cases2016

    • Author(s)
      Yoichi Nishimura, Naoko Fujii, Takahisa Yamamoto et al
    • Journal Title

      Case Reports in Otolaryngology

      Volume: 1 Pages: 1-5

    • DOI

      10.1155/2016/9378428

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] Assessment and Relationship Between Obstructive Sleep Apnea Syndrome and Morphological Changes Caused by Uvulopalatopharyngoplasty2015

    • Author(s)
      Takahisa Yamamoto, Shunpei Shimano, Kohki Kuroda et al
    • Organizer
      TSME 2015 International Conference on Mechanical Engineering
    • Place of Presentation
      Hua Hin (Thailand)
    • Year and Date
      2015-12-17
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] エアロゾル療法における上鼻道へのドラッグデリバリーに関するCFD解析2015

    • Author(s)
      黒田貢規,山本高久,廣瀬貴哉,山本剛
    • Organizer
      第27回バイオエンジニアリング講演会
    • Place of Presentation
      新潟
    • Year and Date
      2015-01-09 – 2015-01-10
    • Related Report
      2014 Research-status Report
  • [Presentation] CFDによる口蓋垂軟口蓋咽頭形成術前後の上気道気流動体解析2015

    • Author(s)
      廣瀬貴哉,黒田貢規,山本高久,中田誠一,藤井直子,西村洋一,鈴木賢二,山本剛
    • Organizer
      第27回バイオエンジニアリング講演会
    • Place of Presentation
      新潟
    • Year and Date
      2015-01-09 – 2015-01-10
    • Related Report
      2014 Research-status Report
  • [Presentation] Computational Fluid Dynamics Simulation for Assessment of Upper Airway Responding to UPPP Surgery in OSAS2014

    • Author(s)
      Takahisa Yamamoto, Kohki Kuroda, Takaya Hirose, Naoko Fujii et al.
    • Organizer
      The 25th International Symposium on Transport Phenomena
    • Place of Presentation
      Thailand
    • Year and Date
      2014-11-05 – 2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] Computational Fluid Dynamics (CFD) in Biomedical Engineering2014

    • Author(s)
      Takahisa yamamoto
    • Organizer
      Workshop on Computational Fluid Dynamics (CFD) in Biomedical Engineering
    • Place of Presentation
      IJN-UTM Cardiovascular Engineering Center
    • Year and Date
      2014-11-03
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] OSASにおける鼻咽頭領域の呼吸解析2014

    • Author(s)
      廣瀬貴哉,山本高久,中田誠一,藤井直子,鈴木賢二,山本剛
    • Organizer
      日本機械学会第26回バイオエンジニアリング講演会
    • Place of Presentation
      東北大学
    • Related Report
      2013 Research-status Report
  • [Presentation] 鼻咽頭領域におけるエアロゾル輸送特性のCFD解析2014

    • Author(s)
      廣瀬貴哉,黒田貢規,山本高久,藤井直子,中田誠一,西村洋一,鈴木賢二,山本剛
    • Organizer
      化学工学会2014春の年会
    • Place of Presentation
      岐阜大学
    • Related Report
      2013 Research-status Report
  • [Presentation] Study on Aerosol Transport Phenomena at Inhalation and Exhalation Periods2014

    • Author(s)
      T. Yamamoto, T. Hirose, K. Kuroda, T. Yamamoto
    • Organizer
      6th World Congress in Biomechanics
    • Place of Presentation
      Boston, USA
    • Related Report
      2013 Research-status Report
  • [Presentation] Computational Fluid Dynamics Simulation for Assessment of Upper Airway Responding to UPPP Surgery in OSAS2014

    • Author(s)
      T. Yamamoto, K. Kuroda, T. Hirose, N. Fujii, Y. Nishimura, S. Nakata, K. Suzuki, T. Yamamoto
    • Organizer
      25th International Symposium on Transport Phenomena
    • Place of Presentation
      Krabi, Thailand
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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