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Functional MRI microscopy in ultra-low field

Research Project

Project/Area Number 25420406
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Measurement engineering
Research InstitutionKinki University (2014-2015)
Toyohashi University of Technology (2013)

Principal Investigator

HATSUKADE Yoshimi  近畿大学, 工学部, 准教授 (90339713)

Co-Investigator(Renkei-kenkyūsha) TANAKA Saburo  豊橋技術科学大学, 工学(系)研究科(研究院), 教授 (10271602)
YOSHIDA Sachiko  豊橋技術科学大学, 工学(系)研究科(研究院), 講師 (40222393)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords超低磁場 / NMR / MRI / SQUID / 磁場耐性 / ノイズ除去 / 計測システム / SQUID磁気センサ / NMR/MRI / 環境磁気 / ノイズキャンセル / 培養細胞 / 機能的MRI / マイクロスコピー
Outline of Final Research Achievements

We aimed to develop an ultra-low-field (ULF) NMR/MRI system, which will be basis of functional MRI microscopy in the future. In this study, an ultra-sensitive SQUID magnetic sensor, which has extremely high sensitivity in low frequency range, which correspond to Larmor frequency in ULF, was used in the ULF NMR/MRI system. Using the system, we showed that the signal amplitude and line width of NMR signal in ULF increased and decreased with the static field intensity, respectively. Achievement of MRI in ULF was also demonstrated. We also studied possibility of realization of ULF NMR/MRI in normal environment, by combining robust SQUID and noise cancelling techniques.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (15 results)

All 2015 2014 2013 Other

All Journal Article (5 results) (of which Peer Reviewed: 5 results) Presentation (9 results) (of which Int'l Joint Research: 1 results) Remarks (1 results)

  • [Journal Article] Robot-based NDE system using movable HTS-SQUID magnetometer covered with HTS film for use in unshielded environment2015

    • Author(s)
      Y. Hatsukade, K. Yoshida, T. Kage, T. Suzuki, S. Tanaka
    • Journal Title

      IEEE Trans. Appl. Supercond.

      Volume: 25 Issue: 3 Pages: 1601105-1601105

    • DOI

      10.1109/tasc.2014.2362847

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mobile HTS-SQUID Magnetometer in an Unshielded Environment2014

    • Author(s)
      廿日出 好,吉田 圭介,鹿毛 孝浩,鈴木 健文,田中 三郎
    • Journal Title

      TEION KOGAKU (Journal of Cryogenics and Superconductivity Society of Japan)

      Volume: 49 Issue: 8 Pages: 439-445

    • DOI

      10.2221/jcsj.49.439

    • NAID

      130004691026

    • ISSN
      0389-2441, 1880-0408
    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Metallic Contaminant Detection System using Multi-Channel Superconducting Quantum Interference Device (SQUID)2014

    • Author(s)
      S. Tanaka, T. Ohtani1, Y. Uchida, T. Chigasaki, and Y. Hatsukade
    • Journal Title

      Solid State Phenomena

      Volume: 215 Pages: 465-469

    • DOI

      10.4028/www.scientific.net/ssp.215.465

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] ULF-NMR system using HTS-SQUID and permanent magnet2013

    • Author(s)
      S. Fukumoto
    • Journal Title

      Physica C

      Volume: 484 Pages: 202-205

    • DOI

      10.1016/j.physc.2012.03.014

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] pplication of ultra-low field HTS-SQUID NMR/MRI to contaminant detection in food2013

    • Author(s)
      Y. Hatsukade
    • Journal Title

      IEEE Trans. Appl. Supercond

      Volume: 23 Issue: 3 Pages: 1602204-1602204

    • DOI

      10.1109/tasc.2012.2237473

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] NDE System Utilizing Robust HTS-SQUID Magnetometer for Use in Unshielded Environments2015

    • Author(s)
      Y. Hatsukade, S. Tanaka
    • Organizer
      European Conference on Applied Superconductivity 2015 (EUCAS2015)
    • Place of Presentation
      Lyon, France
    • Year and Date
      2015-09-06
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 高磁場耐性HTS-SQUIDマグネトメータを用いた非破壊検査装置の開発2015

    • Author(s)
      廿日出好,田中三郎
    • Organizer
      電子情報通信学会 超伝導エレクトロニクス研究会
    • Place of Presentation
      機械振興会館,東京
    • Year and Date
      2015-01-22
    • Related Report
      2014 Research-status Report
  • [Presentation] 高磁場耐性HTS-SQUIDの開発 -SQUID特性に関する研究-2014

    • Author(s)
      廿日出好,鈴木健文,田中三郎
    • Organizer
      2014年秋季低温工学・超電導学会
    • Place of Presentation
      コラッセふくしま,福島
    • Year and Date
      2014-11-06
    • Related Report
      2014 Research-status Report
  • [Presentation] 高磁場耐性HTS-SQUIDの開発 -非破壊検査への応用-2014

    • Author(s)
      廿日出好,鈴木健文,田中三郎
    • Organizer
      2014年秋季低温工学・超電導学会
    • Place of Presentation
      コラッセふくしま,福島
    • Year and Date
      2014-11-06
    • Related Report
      2014 Research-status Report
  • [Presentation] Robot-based NDE system using movable HTS SQUID magnetometer covered with HTS film for use in unshielded environment2014

    • Author(s)
      Y. Hatsukade, K. Yoshida, T. Kage, T. Suzuki, S. Tanaka
    • Organizer
      Applied Superconductivity Conference 2014
    • Place of Presentation
      Charllote, NC, USA
    • Year and Date
      2014-08-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of Metallic Contaminant Detection System using rf High-Tc SQUIDs for food inspection2014

    • Author(s)
      S. Tanaka, Y. Hatsukade,T. Ohtani and S. Suzuki
    • Organizer
      Applied Superconductivity Conference 2014
    • Place of Presentation
      Charllote, NC, USA
    • Year and Date
      2014-08-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Development of Contaminant Detection System Based on Ultra-Low Field NMR/MRI

    • Author(s)
      S. Tsunaki, M. Yamanoto, Y. Hatsukade, S. Tanaka
    • Organizer
      11th European Conference on Applied Superconductivity
    • Place of Presentation
      Genova, Italy
    • Related Report
      2013 Research-status Report
  • [Presentation] HTS-SQUIDを用いた超低磁場NMR/MRI装置の食品検査応用

    • Author(s)
      山本将彰,綱木辰悟,豊田裕智,八田純一,廿日出好,田中三郎
    • Organizer
      第61回応用物理学会春季学術講演会
    • Place of Presentation
      青山学院大学、神奈川県
    • Related Report
      2013 Research-status Report
  • [Presentation] LC共振器を用いた超低磁場NMR/MRIに関する研究

    • Author(s)
      豊田裕智,山本将彰,綱木辰悟,八田純一,廿日出好,田中三郎
    • Organizer
      第61回応用物理学会春季学術講演会
    • Place of Presentation
      青山学院大学、神奈川県
    • Related Report
      2013 Research-status Report
  • [Remarks] Publication List

    • URL

      http://ens.tut.ac.jp/squid/pub/paper.html

    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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