Functional MRI microscopy in ultra-low field
| Project/Area Number |
25420406
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Multi-year Fund |
|---|
| Section | 一般 |
|---|
| Research Field |
Measurement engineering
|
|---|
| Research Institution | Kinki University (2014-2015)
Toyohashi University of Technology (2013) |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
TANAKA Saburo 豊橋技術科学大学, 工学(系)研究科(研究院), 教授 (10271602)
YOSHIDA Sachiko 豊橋技術科学大学, 工学(系)研究科(研究院), 講師 (40222393)
|
|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
|
|---|
| Keywords | 超低磁場 / NMR / MRI / SQUID / 磁場耐性 / ノイズ除去 / 計測システム / SQUID磁気センサ / NMR/MRI / 環境磁気 / ノイズキャンセル / 培養細胞 / 機能的MRI / マイクロスコピー |
|---|
| Outline of Final Research Achievements |
We aimed to develop an ultra-low-field (ULF) NMR/MRI system, which will be basis of functional MRI microscopy in the future. In this study, an ultra-sensitive SQUID magnetic sensor, which has extremely high sensitivity in low frequency range, which correspond to Larmor frequency in ULF, was used in the ULF NMR/MRI system. Using the system, we showed that the signal amplitude and line width of NMR signal in ULF increased and decreased with the static field intensity, respectively. Achievement of MRI in ULF was also demonstrated. We also studied possibility of realization of ULF NMR/MRI in normal environment, by combining robust SQUID and noise cancelling techniques.
|
Report
(4 results)
Research Products
(15 results)
