Odorant cluster sensing based on molecular profile recognition materials

• Project/Area Number: 25420409
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Measurement engineering
• Research Institution: Kyushu University
• Principal Investigator: Liu Chuanjun 九州大学, 味覚・嗅覚センサ研究開発センター, 准教授 (70599654)
• Co-Investigator(Renkei-kenkyūsha): HAYASHI KENSHI 九州大学, システム情報科学研究院, 教授 (50202263)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000); Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000); Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000); Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
• Keywords: 匂いセンサ / 分子インプリント / クラスターセンシング / バイオミメティック / QCMセンサアレイ / 多変量解析 / ソルゲル / センサアレイ / QCM / データ解析 / 分子プロファイル識別 / 匂い吸着分離 / パターン認識 / 嗅覚

Outline of Final Research Achievements

A bioinspired odorant cluster sensing system was developed to imitate the olfactory sensory. A variety of molecular profile recognition materials were prepared by using molecular imprinting (MIP) technique. Their recognition ability was confirmed by GC/MS measurement and QCM sensing. The cluster sensing system was fabricated by the integration of a MIPs-loaded absorption/desorption modules and metal oxide semiconductor gas sensors based sensing modules. The system succeeded in the detection and recognition of odorants with different molecular profiles. The clustering of odorants based on molecular parameters was carried out by using different analysis approaches, among which t-distributed stochastic neighbor embedding (t-SNE) showed a good result in the odorant clustering. The above accomplishments make it possible to design sensor systems to detect odor in a way close to the olfactory perception.

Research Products

• [Journal Article] Preparation of Fluorescent Molecularly Imprinted Polymer Micropowder for Odorant Visualization (2016)
  • Author(s): K. Iwata, S. Yamashita, H. Yoshioka, C. Liu, K. Hayashi
  • Journal Title: Sensors and Materials Volume: 28 Pages: 173-179
  • DOI: 10.18494/SAM.2016.1167
  • ISSN: 0914-4935, 2435-0869
  • Peer Reviewed
• [Journal Article] Localized Surface Plasmon Resonance Gas Sensor based on Molecularly Imprinted Polymer Coated Au Nano-island Films: Influence of Nanostructure on Sensing Characteristics (2016)
  • Author(s): B. Chen, C. Liu, Y. Xie, K. Hayashi
  • Journal Title: IEEE Sensors Journal Volume: 99 Issue: 10 Pages: 1-4
  • DOI: 10.1109/jsen.2016.2536629
  • Peer Reviewed / Int'l Joint Research
• [Journal Article] 分子鋳型フィルタ吸着剤による匂いクラスタリング (2015)
  • Author(s): 千代丸瑶、篠原翔、劉傳軍、林健司
  • Journal Title: 信学技報 Volume: 114 Pages: 77-82
• [Journal Article] 匂い可視化のための分子認識能を持つ蛍光ナノビーズの開発 (2015)
  • Author(s): 岩田和也、吉岡大貴、劉傳軍、林健司
  • Journal Title: 信学技報 Volume: 114 Pages: 83-88
• [Journal Article] Molecular imprinted polyacrylic acids based QCM sensor array for recognition of organic acids in body odor (2014)
  • Author(s): S.K. Jha, C. Liu, K. Hayashi
  • Journal Title: Sensors and Actuators B : Chemical Volume: 204 Pages: 74-87
  • DOI: 10.1016/j.snb.2014.07.098
  • Peer Reviewed
• [Journal Article] Selective Terpene Vapor Detection Using Molecularly Imprinted Polymer Coated Au Nanoparticle LSPR Senor (2014)
  • Author(s): B. Chen, C. Liu, K. Hayashi
  • Journal Title: IEEE Sensor Journal Volume: 14 Issue: 10 Pages: 3458-3464
  • DOI: 10.1109/jsen.2014.2346187
  • Peer Reviewed
• [Journal Article] Odor Filtering and Sensing System Based Artificial Nose for Chemical Vapor Class Recognition (2014)
  • Author(s): S.K. Jha, Y. Chiyomaru, M. Imahashi, C. Liu, K. Hayashi
  • Journal Title: Sensor Letters Volume: 12 Issue: 1 Pages: 1-16
  • DOI: 10.1166/sl.2014.3217
  • Peer Reviewed
• [Journal Article] Molecularly Imprinted Polymer Coated Au Nanoparticle Sensor for α-pinene Vapor Detection (2013)
  • Author(s): B. Chen, C. Liu, X. Sun, K. Hayashi
  • Journal Title: Sensors, IEEE Volume: 2013 Pages: 117-120
  • DOI: 10.1109/icsens.2013.6688152
  • Peer Reviewed
• [Presentation] Molecularly Imprinted Polymer Nanobeads Based QCM Sensor Array for Volatile Organic Acid Detection (2016)
  • Author(s): C. Liu, H. Yoshioka, H. Wang, K. Hayashi
  • Organizer: The 16th International Meeting on Chemical Sensors
  • Place of Presentation: Jeju Island, Korea
  • Year and Date: 2016-07-10
  • Int'l Joint Research
• [Presentation] Molecularly imprinted sol-gel based on LSPR sensor for fatty acid vapor detection (2016)
  • Author(s): L. Shang, C. Liu, K. Hayshi
  • Organizer: The 16th International Meeting on Chemical Sensors
  • Place of Presentation: Jeju Island, Korea
  • Year and Date: 2016-07-10
  • Int'l Joint Research
• [Presentation] Development of Molecular Recognition Materials for Bioinspired Odor Cluster Sensing (2014)
  • Author(s): C. Liu, K. Hayashi
  • Organizer: Second World Congress of the Digital Olfactory Society
  • Place of Presentation: Tokyo, Japan
  • Year and Date: 2014-12-08 – 2014-12-09
• [Presentation] 分子インプリントポリマーを用いた蛍光ナノビーズによる匂いの可視化 (2014)
  • Author(s): 岩田和也，吉岡大貴，劉傳軍，林健司
  • Organizer: 平成２６年度応用物理学会九州支部学術講演会
  • Place of Presentation: 大分
  • Year and Date: 2014-12-06 – 2014-12-07
• [Presentation] 吸着特性調整及び高機能性吸着剤の開発による匂い測定 (2014)
  • Author(s): 千代丸瑶，劉傳軍，林健司
  • Organizer: 平成２６年（第６７回）電気・情報関係学会九州支部連合大会
  • Place of Presentation: 鹿児島
  • Year and Date: 2014-09-18 – 2014-09-19
• [Presentation] Molecular Imprinted Polyacrylic Acids Coated QCM Sensor Array For Recognition Of Organic Acid Odors (2014)
  • Author(s): S.K. Jha, C. Liu, K. Hayashi
  • Organizer: The 7th Asia-Pacific Conference on Transducers and Micro/Nano Technologies
  • Place of Presentation: Daegu, Korea
  • Year and Date: 2014-06-29 – 2014-07-02
• [Presentation] Molecular Imprinted Polyacrylic Acids Based QCM Sensor Arrays for Recognition of Organic Acids Odors (2014)
  • Author(s): S. K. Jha, C. Liu, K. Hayashi
  • Organizer: APCOT2014
  • Place of Presentation: Daegu, Korea
• [Presentation] Detection of Volatile Fatty Acids by Using MIP Coated QCM Sensor Array (2014)
  • Author(s): S. K. Jha, M. Imahashi, C. Liu, K. Hayashi
  • Organizer: IUMRS-ICA 2014
  • Place of Presentation: Fukuoka, Japan
• [Presentation] 分子インプリントポリマーを利用した蛍光マイクロ粒子による匂いの可視化 (2014)
  • Author(s): 岩田和也、横山諒平、今橋理広、劉傳軍、林健司
  • Organizer: 平成２６年度電気学会全国大会
  • Place of Presentation: 松山
• [Book] Smart Sensors and Systems, Part Ⅲ Gas and Odor Sensing, Odor Sensing Technologies for Visualization of Odor Quality and Space (2015)
  • Author(s): C. Liu, K. Hayashi
  • Total Pages: 467
  • Publisher: Springer International Publishing Switzerland
• [Remarks] 九州大学・システム情報科学研究院・情報エレクトロニクス部門・有機電子デバイス研究室
  • URL: http://o.ed.kyushu-u.ac.jp/oedlab/Welcome.html
• [Remarks] 九州大学／システム情報科学研究院／情報エレクトロニクス部門／有機電子デバイス研究室
  • URL: http://o.ed.kyushu-u.ac.jp/oedlab/research.html