Evaluation of novel medical devices developed by rapid formation of apatite layer on polymer substrate
| Project/Area Number |
25420736
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Composite materials/Surface and interface engineering
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| Research Institution | Sophia University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
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| Keywords | ポリエーテルエーテルケトン / 真空紫外光照射 / 表面改質 / マイクロ波加熱 / 水酸アパタイト / シランカップリング / 接着強化 / 親水性 / 水酸アパタイト膜 / 膜厚 / メッシュ / 硫酸処理 / 水酸アパタイト被覆 / 生体材料 / シリカ質膜 / 疑似体液 |
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| Outline of Final Research Achievements |
Rapid formation of biocompatible hydroxyapatite (Ca10(PO4)6(OH)2; HAp) layer on the polyetheretherketone (PEEK) substrate for a spinal fusion implant was examined. The process in this research included: (i) the surface modification of PEEK through the vacuum ultraviolet (VUV) irradiation (wavelength: 172 nm) or acid treatment, (ii) the immersion of surface-modified PEEK substrate into the HAp-dissolved solution (the dissolution of HAp powder into the de-ionized water with bubbling of CO2 gas at room temperature for 1 h), and (iii) the microwave heating at 100 ～ 140°C for 10 min to form HAp layer on the PEEK substrate.
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Report
(4 results)
Research Products
(17 results)
