| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
We previously developed hydroxyapatite (HAp) and octacalcium phosphate (OCP) coatings to control the corrosion of bioabsorbable/biodegradable magnesium (Mg) alloys. In this study, polymer and calcium phosphate (Ca-P) composite coatings were formed to prevent local corrosion of Ca-P-coated Mg alloy. First, poly-L-lactic acid (PLLA) and polycaprolactone (PCL) were used, but these hydrophobic polymers did not show enough adhesiveness to Ca-P coating, leading to the corrosion under the polymer layer. Hydrophilic polymer (HPpolym) and Ca-P composite coating showed slightly lower corrosion protectiveness than Ca-P coating. An interesting finding of this study was that HPpolym coating improved corrosion resistance of Mg alloy in cell culture medium.
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