Development of anti-local corrosion apatite-biodegradable polymer composite coatings for bioabsorbable Mg alloys
| Project/Area Number |
25420742
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Composite materials/Surface and interface engineering
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| Research Institution | National Institute for Materials Science |
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Principal Investigator |
Hiromoto Sachiko 国立研究開発法人物質・材料研究機構, 生体機能材料ユニット, MANA研究者 (00343880)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,810,000 (Direct Cost: ¥3,700,000、Indirect Cost: ¥1,110,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | マグネシウム / リン酸カルシウム / 生分解性高分子 / 複合化被膜 / 親疎水性 / 腐食 / 疑似体液 / 水酸アパタイト / 複合化 / 耐食被膜 / 変形 / 複合被膜 / 腐食防食 / 密着性 / 耐き裂性 / 生体材料 |
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| Outline of Final Research Achievements |
We previously developed hydroxyapatite (HAp) and octacalcium phosphate (OCP) coatings to control the corrosion of bioabsorbable/biodegradable magnesium (Mg) alloys. In this study, polymer and calcium phosphate (Ca-P) composite coatings were formed to prevent local corrosion of Ca-P-coated Mg alloy. First, poly-L-lactic acid (PLLA) and polycaprolactone (PCL) were used, but these hydrophobic polymers did not show enough adhesiveness to Ca-P coating, leading to the corrosion under the polymer layer. Hydrophilic polymer (HPpolym) and Ca-P composite coating showed slightly lower corrosion protectiveness than Ca-P coating. An interesting finding of this study was that HPpolym coating improved corrosion resistance of Mg alloy in cell culture medium.
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Report
(4 results)
Research Products
(20 results)
