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Unified computational model of motor control based on spatial representation and understanding of neural activities in motor-related brain network

Research Project

Project/Area Number 25430007
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurophysiology / General neuroscience
Research InstitutionJapan Advanced Institute of Science and Technology

Principal Investigator

Tanaka Hirokazu  北陸先端科学技術大学院大学, 先端科学技術研究科, 准教授 (00332320)

Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords計算論モデル / 脳科学 / 神経科学 / 運動制御 / 感覚処理 / 最適制御 / 最適推定 / 内部モデル / 計算論的神経科学 / 第一次運動野 / 前頭頭頂運動ネットワーク / 神経活動 / 視覚運動変換 / 到達運動 / 運動適応 / 小脳 / 空間ベクトル表現
Outline of Final Research Achievements

I proposed a computational model of the primary motor cortex (M1) in which visuomotor transformation is solved through Newton-Euler dynamics with spatial representations, and explained a variety of findings about M1 neural properties in a unified way. In addition to neural properties, the model also explained various findings from human psychophysics of motor adaptation such as generalization patterns. Extending the model of M1, I attempted to construct a model of the motor-related network including the parietal cortex and the cerebellum. Especially, I discovered, by constructing a model of cerebellar activities, a predictive computation from inputs of the mossy fibers to outputs of the cerebeller nuclei. With these models, I clarified the neural representations and the algorithms with which the brain predicts and controls body movements.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (42 results)

All 2016 2015 2014 2013 Other

All Int'l Joint Research (1 results) Journal Article (7 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 6 results,  Open Access: 2 results,  Acknowledgement Compliant: 3 results) Presentation (27 results) (of which Int'l Joint Research: 11 results,  Invited: 16 results) Remarks (6 results) Funded Workshop (1 results)

  • [Int'l Joint Research] Salk Institute/University of California, San Diego(米国)

    • Related Report
      2015 Research-status Report
  • [Journal Article] The Meaning of "Understanding the Brain": Peeking into the Brain of a Computational Neuroscientist2016

    • Author(s)
      田中宏和
    • Journal Title

      BRAIN and NERVE

      Volume: 68 Issue: 11 Pages: 1379-1384

    • DOI

      10.11477/mf.1416200601

    • ISSN
      1344-8129, 1881-6096
    • Year and Date
      2016-11-01
    • Related Report
      2016 Annual Research Report
  • [Journal Article] Modeling the motor cortex: Optimality, recurrent neural networks, and spatial dynamics2016

    • Author(s)
      Tanaka, H.
    • Journal Title

      Neuroscience Research

      Volume: 104 Pages: 64-71

    • DOI

      10.1016/j.neures.2015.10.012

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Coordinate Systems in the Motor System: Computational Modeling and EEG Experiment2016

    • Author(s)
      Tanaka, H., Miyakoshi, M., & Makeig, S.
    • Journal Title

      Advances in Cognitive Neurodynamics

      Volume: V Pages: 85-92

    • DOI

      10.1007/978-981-10-0207-6_14

    • ISBN
      9789811002052, 9789811002076
    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Coordinate Systems in the Motor System: Computational Modeling and EEG experiment2015

    • Author(s)
      Tanaka H., Miyakoshi M. & Makeig S.
    • Journal Title

      The 5th International Conference on Cognitive Neurodynamics 2015 (ICCN 2015)

      Volume: 印刷中

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Motor adaptation and generalization of reaching movements using motor primitives based on spatial coordinates2014

    • Author(s)
      Tanaka, H., & Sejnowski, T. J.
    • Journal Title

      Journal of Neurophysiology

      Volume: なし Issue: 4 Pages: 1-5

    • DOI

      10.1152/jn.00002.2014

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Task-related oxygenation and cerebral blood volume changes estimated from NIRS signals in motor and cognitive tasks2014

    • Author(s)
      Tanaka H., Katura T., H. Sato
    • Journal Title

      NeuroImage

      Volume: 94 Pages: 107-119

    • DOI

      10.1016/j.neuroimage.2014.02.036

    • NAID

      120005526725

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Computing reaching dynamics in motor cortex with Cartesian spatial coordinates2013

    • Author(s)
      Tanaka H., Sejnowski T.J.
    • Journal Title

      Journal of Neurophysiology

      Volume: 109 Issue: 4 Pages: 1182-1201

    • DOI

      10.1152/jn.00279.2012

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Dynamics of directional tuning and reference frames in humans: A high-density EEG study2016

    • Author(s)
      Tanaka H., Miyakoshi M., & Makeig S.
    • Organizer
      Neuroscience 2016 Annual Meeting
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Directionally tuned signals in human EEG during step-tracking wrist movement2016

    • Author(s)
      Kambara, H., Tanaka, H., Miyakoshi M., Yoshimura, N., Koike, Y., Makeig S.
    • Organizer
      Neuroscience 2016 Annual Meeting
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2016-11-12
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Directional tuning and reference frames revealed by noninvasive EEG in humans: a computational MoBI study2016

    • Author(s)
      Tanaka H.
    • Organizer
      The 31st International Congress of Psychology
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-07-24
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Dynamics of directional tuning and reference frames in humans: A mobile brain/body imaging study2016

    • Author(s)
      Tanaka H.
    • Organizer
      The Japan-Europe International Meeting about Embodied Brain
    • Place of Presentation
      Taormina, Italy
    • Year and Date
      2016-05-30
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Temporal dynamics of directional tuning and reference frames in human reaching task revealed with high-density EEG2016

    • Author(s)
      Tanaka H.
    • Organizer
      The 1st International Symposium on Embodied-Brain Systems Science (EmboSS 2016)
    • Place of Presentation
      東京大学(東京都文京区)
    • Year and Date
      2016-05-08
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Directional tuning and reference frames revealed by noninvasive EEG in humans: a computational MoBI study2016

    • Author(s)
      Tanaka H.
    • Organizer
      第55回日本生体医工学会大会
    • Place of Presentation
      富山国際会議場(富山県富山市)
    • Year and Date
      2016-04-26
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Mobile Brain/Body Imaging for Natural Movements2016

    • Author(s)
      Tanaka H.
    • Organizer
      MoBI (Mobile Brain/Body Imaging) Workshop
    • Place of Presentation
      San Diego, U.S.A.
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Is movement duration predetermined in visually guided reaching? A comparison of finite- and infinite-horizon optimal feedback control2015

    • Author(s)
      Li L., Imamizu H. and Tanaka H.
    • Organizer
      International Conference on Advanced Mechatronics (ICAM) 2015
    • Place of Presentation
      Waseda University, Tokyo, Japan
    • Year and Date
      2015-12-06
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Formation of internal forward model with sensory and reward prediction errors: A behavioral confirmation2015

    • Author(s)
      Satou H., Sasaki A., Nozaki D. and Tanaka H
    • Organizer
      International Conference on Advanced Mechatronics (ICAM) 2015
    • Place of Presentation
      Waseda University, Tokyo, Japan
    • Year and Date
      2015-12-06
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] How motor cortex represents body movements: Optimality, recurrent neural networks and spatial dynamics2015

    • Author(s)
      Tanaka, H., Miyakoshi, M., & Makeig, S.
    • Organizer
      IEEE The 24th International Symposium on Robot and Human Interactive Communication (RO-MAN)
    • Place of Presentation
      Kobe Convention Center, Kobe, Japan
    • Year and Date
      2015-08-31
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Movement Representation in the Motor System: Computational Modeling and EEG experiment2015

    • Author(s)
      Tanaka, H., Miyakoshi, M., & Makeig, S.
    • Organizer
      Brain Connectivity Workshop 2015
    • Place of Presentation
      San Diego, U.S.A.
    • Year and Date
      2015-06-12
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Coordinate Systems in the Motor System: Computational Modeling and EEG experiment2015

    • Author(s)
      Tanaka, H., Miyakoshi, M., & Makeig, S.
    • Organizer
      The 5th International Conference on Cognitive Neurodynamics
    • Place of Presentation
      Sanya, China
    • Year and Date
      2015-06-04
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 到達運動の運動方程式と頭頂前頭運動野の座標系2015

    • Author(s)
      田中 宏和
    • Organizer
      第92回日本生理学学会 第120回日本解剖学会 合同大会、神戸国際会議場
    • Place of Presentation
      神戸国際会議場 兵庫県 神戸市
    • Year and Date
      2015-03-21
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Computing Reaching Dynamics in Motor Cortex with Cartesian Spatial Coordinates2014

    • Author(s)
      田中 宏和
    • Organizer
      Fetz博士記念シンポジウム - Frontier of Systems Neuroscience of Motor Control(運動制御にかかわるシステム神経科学の最前線)
    • Place of Presentation
      国立精神・神経医療センター 東京都 小平市
    • Year and Date
      2014-09-14
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 第一次運動野は空間ベクトルを用いて到達運動ダイナミクスを計算する2014

    • Author(s)
      田中 宏和
    • Organizer
      SICE中部支部制御理論研究委員会ワーキングセミナー
    • Place of Presentation
      名古屋大学 東山キャンパス 愛知県 名古屋市
    • Year and Date
      2014-09-11
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] Directional tuning and reference frames revealed by non-invasive EEG in humans2014

    • Author(s)
      田中 宏和
    • Organizer
      第8回モーターコントロール研究会
    • Place of Presentation
      筑波大学 茨城県 つくば市
    • Year and Date
      2014-08-09
    • Related Report
      2014 Research-status Report
  • [Presentation] Directional tuning and reference frames revealed by non-invasive EEG in humans2014

    • Author(s)
      田中 宏和
    • Organizer
      Organization of Human Brain Mapping 2014 Annual Meeting
    • Place of Presentation
      Hamburg, Germany
    • Year and Date
      2014-06-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Task-related component analysis for fuctional neuroimaging2013

    • Author(s)
      Tanaka H., Katura T., Sato H.
    • Organizer
      Mobile Brain/Body Imaging (MoBI) Workshop
    • Place of Presentation
      Delmenhorst, Germany
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] Motor cortex computes reaching dynamics using Cartesian spatial coordinates2013

    • Author(s)
      Tanaka H., Sejnowski T.J.
    • Organizer
      Mobile Brain/Body Imaging (MoBI) Workshop
    • Place of Presentation
      Delmenhorst, Germany
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 第一次運動野は空間ベクトルを用いて到達運動ダイナミクスを計算する

    • Author(s)
      田中宏和, Terrence J Sejnowski
    • Organizer
      視覚科学統合研究センターシンポジウム「視覚情報処理の新展開ー局所回路から認知へ」
    • Place of Presentation
      立命館大学 びわこキャンパス
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] アンダーサンプリングNIRS信号からの瞬時心拍数測定法

    • Author(s)
      田中宏和、小幡亜希子、桂卓成
    • Organizer
      第16回日本ヒト脳機能マッピング学会
    • Place of Presentation
      仙台国際ホテル
    • Related Report
      2013 Research-status Report
  • [Presentation] 田中宏和、桂卓成、佐藤大樹

    • Author(s)
      脱酸素化ヘモグロビンの共変動を用いた課題関連成分分析による血液量と血中酸素濃度変化の推定法
    • Organizer
      第16回日本ヒト脳機能マッピング学会
    • Place of Presentation
      仙台国際ホテル
    • Related Report
      2013 Research-status Report
  • [Presentation] 第一次運動野は空間ベクトルを用いて到達運動ダイナミクスを計算する

    • Author(s)
      田中宏和, Terrence J Sejnowski
    • Organizer
      脳と心のメカニズム 第14回冬のワークショップ
    • Place of Presentation
      北海道 ルスツ
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 第一次運動野は何を表現し計算しているのか

    • Author(s)
      田中宏和
    • Organizer
      Autumn School of Computational Neuroscience (ASCONE)
    • Place of Presentation
      長野 諏訪
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 運動野の情報表現ー計算論的モデルー

    • Author(s)
      田中宏和
    • Organizer
      身体性基盤研究会
    • Place of Presentation
      東北大学 電気通信研究所
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] 課題関連成分分析法によるNIRS信号のヘモダイナミクス反応成分と全身性変動成分の課題および刺激応答性

    • Author(s)
      田中宏和、桂卓成、佐藤大樹
    • Organizer
      第15回日本ヒト脳機能マッピング学会
    • Place of Presentation
      東京大学
    • Related Report
      2013 Research-status Report
  • [Presentation] Understanding movement representations in the motor cortex for functional recovery

    • Author(s)
      Tanaka H., Sejnowski T.J.
    • Organizer
      Neuro2013 公募シンポジウム「計算論的間隔運動制御とリハビリテーションの統合」
    • Place of Presentation
      京都国際会議場
    • Related Report
      2013 Research-status Report
  • [Remarks] 北陸先端科学技術大学院大学 研究者紹介

    • URL

      https://www.jaist.ac.jp/profiles/info.php?profile_id=592

    • Related Report
      2016 Annual Research Report
  • [Remarks] 研究紹介 youtube チャンネル

    • URL

      https://www.youtube.com/user/ht2022columbia

    • Related Report
      2016 Annual Research Report
  • [Remarks] 計算論的神経科学研究室

    • URL

      http://www.jaist.ac.jp/~hirokazu/Site/Welcome.html

    • Related Report
      2014 Research-status Report
  • [Remarks] 計算論的神経科学YouTubeチャンネル

    • URL

      https://www.youtube.com/user/ht2022columbia

    • Related Report
      2014 Research-status Report
  • [Remarks] 計算論的神経科学研究室

    • URL

      http://www.jaist.ac.jp/~hirokazu/Site/Welcome.html

    • Related Report
      2013 Research-status Report
  • [Remarks] 計算論的神経科学YouTubeチャンネル

    • URL

      https://www.youtube.com/user/ht2022columbia

    • Related Report
      2013 Research-status Report
  • [Funded Workshop] IEEE The 24th International Symposium on Robot and Human Interactive Communication (RO-MAN)2015

    • Place of Presentation
      Kobe Convention Center, Kobe, Japan
    • Year and Date
      2015-08-31
    • Related Report
      2015 Research-status Report

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Published: 2014-07-25   Modified: 2022-01-24  

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