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Awareness and attention in animal models of blindsight and spatial neglect

Research Project

Project/Area Number 25430022
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurophysiology / General neuroscience
Research InstitutionNational Institute for Physiological Sciences

Principal Investigator

Yoshida Masatoshi  生理学研究所, 発達生理学研究系, 助教 (30370133)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords視覚的気づき / 視覚的注意 / 盲視 / サリエンシー / 半側空間無視 / 上側頭回 / 空間認知 / 神経科学 / 注意 / 視覚探索 / 眼球運動
Outline of Final Research Achievements

The aim of this research is to establish an animal model of spatial neglect. For this purpose, we made a lesion in the right superior temporal gyrus and evaluated their behavior with a target-selection task and eye-tracking. We found that neglect-like behavior was sustained for more than 1 month after the lesion. Thus we conclude that we established an animal model of spatial neglect. We also measured BOLD activity of the same monkeys before and after the lesion and found that the functional connectivity within the attention network is reduced and recovered, which was correlated with behavioral markers of spatial neglect after the lesion.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (13 results)

All 2016 2015 2014 Other

All Int'l Joint Research (1 results) Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Open Access: 3 results) Presentation (6 results) (of which Int'l Joint Research: 2 results,  Invited: 4 results) Remarks (1 results)

  • [Int'l Joint Research] チュービンゲン大学(ドイツ)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] A Microsaccadic Account of Attentional Capture and Inhibition of Return in Posner Cueing.2016

    • Author(s)
      Tian X, Yoshida M, Hafed ZM
    • Journal Title

      Frontiers in systems neuroscience

      Volume: 10 Pages: 23-23

    • DOI

      10.3389/fnsys.2016.00023

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Signal detection analysis of blindsight in monkeys.2015

    • Author(s)
      Yoshida M, Isa T
    • Journal Title

      Scientific reports

      Volume: 5 Issue: 1 Pages: 10755-10755

    • DOI

      10.1038/srep10755

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Applying differential evolution MCMC to parameterize large-scale spiking neural simulations2015

    • Author(s)
      R Veale, T Isa, M Yoshida
    • Journal Title

      Proceedings of 2015 IEEE Congress on Evolutionary Computation (CEC)

      Volume: - Pages: 1620-1627

    • DOI

      10.1109/cec.2015.7257081

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Large-scale spiking circuit simulation of spatio-temporal dynamics in superior colliculus2014

    • Author(s)
      Richard E Veale, Tadashi Isa, Masatoshi Yoshida
    • Journal Title

      BMC Neuroscience

      Volume: 15(Suppl 1) Issue: S1

    • DOI

      10.1186/1471-2202-15-s1-p4

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Saliency-guided neural prosthesis for visual attention: design and simulation.2014

    • Author(s)
      Masatoshi Yoshida & Richard Veale
    • Journal Title

      Neuroscience Research

      Volume: 78 Pages: 90-94

    • DOI

      10.1016/j.neures.2013.07.007

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] Awareness in Blindsight in Man and Monkey.2016

    • Author(s)
      吉田 正俊
    • Organizer
      8th Annual meeting of The UK Neuro-Ophthalmology Special Interest Group
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2016-03-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Awareness and saliency in blindsight.2015

    • Author(s)
      吉田 正俊
    • Organizer
      International Symposium on Consciousness and Intention in Economics and Philosophy
    • Place of Presentation
      京都府、京都市
    • Year and Date
      2015-12-12
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Awareness in Blindsight in Man and Monkey.2015

    • Author(s)
      吉田 正俊
    • Organizer
      Symposium on Memory and Mind
    • Place of Presentation
      宮城県、仙台市
    • Year and Date
      2015-09-29
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] Vision and eye movements in blindsight.2015

    • Author(s)
      吉田 正俊
    • Organizer
      the 31st International Pupil Colloquium 2015
    • Place of Presentation
      Oxford, UK
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] サリエンシーの脳内メカニズム2014

    • Author(s)
      吉田正俊
    • Organizer
      日本神経科学大会
    • Place of Presentation
      パシフィコ横浜 (神奈川県横浜市)
    • Year and Date
      2014-09-13
    • Related Report
      2014 Research-status Report
  • [Presentation] Large Scale Spiking Neuron Models of Superior Colliculus2014

    • Author(s)
      Richard Veale, Tadashi Isa & Masatoshi Yoshida
    • Organizer
      the 24th Annual Meeting of the Society for the Neural Control of Movement
    • Place of Presentation
      NH Krasnapolsky Hotel, Amsterdam, Nederland
    • Related Report
      2013 Research-status Report
  • [Remarks] 「見えてないのに分かってしまう」盲視はヒトでもサルでも同じ

    • URL

      http://www.nips.ac.jp/release/2015/06/post_298.html

    • Related Report
      2015 Annual Research Report

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Published: 2014-07-25   Modified: 2019-07-29  

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