| Project/Area Number |
25430034
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Nerve anatomy/Neuropathology
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| Research Institution | University of Fukui |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Hiroshi 福井大学, 工学(系)研究科(研究院), 教授 (80377473)
MURASE Kazuyuki 福井大学, 工学(系)研究科(研究院), 教授 (40174289)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 局所神経回路 / 聴覚 / シナプス / 機能イメージング / 分子局在 / 傍細胞記録染色法 / in vivo calcium imaging / c-fos / juxtacecellular staining / juxtacellular staining |
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| Outline of Final Research Achievements |
Natural sounds are always complex in a temporal aspect, and our brain must have specialized neural circuitry which is involved in the analysis of such complex sound, although the anatomical and physiological basis of the analysis is poorly known. In this study, we studied the input and output properties of local circuit of the inferior colliculus, which is the first integration center of many aspects of auditory information, with combination of physiological and anatomical techniques at a single cell level. From the results, in the inferior colliculus auditory information is represented not only by spatial assembly of each neurons but also by cell types. The data also suggested that some of the responsiveness to complex sounds is created de novo by local circuitry of the inferior colliculus.
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