| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Outline of Final Research Achievements |
The side-chain aromatic rings of phenylalanine and tyrosine residues in the interior of protein frquenty rotate about their Cb-Cg axis, which is assumed to occur when the protein undergoes a large amplitude slow breathing motion. In this project, uder varied hydrotatic pressures, the ring flipping rates were evaluated by using the SAIL-NMR methds. This study expectedly provides new insight into the large amplitude motion of proteins.
|
