| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
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| Outline of Final Research Achievements |
The use of anomalous dispersion of X-ray (resonant X-ray scattering) is expected to serve us a new insight on functional structures of proteins and membrane in solutions, especially of metalloproteins proteins containing metal atoms or clusters that are involved in a wide range of important biological processes. On the other hand, the recent development of the wide-angle X-ray scattering technique of proteins and membrane using third-generation synchrotron sources shows us that the X-ray solution scattering enables to observe a whole hierarchical structure ranging from ~0.2 nm to ~250 nm, namely, from the secondary structure to the quaternary one of proteins or from the alkylchain packing to the whole structure of lipid aggregate.
The aim of this study was the development of the new method for studying the internal structure of biological material in-situ by the combination of resonant and wide-angle scattering of X-ray.
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