| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Outline of Final Research Achievements |
The cyclostome lampreys, a group of vertebrates that diverged early in evolution, retain various ancestral morphological features. In order to clarify the evolutionary pathway of origin and developmental behavior of undifferentiated precursor cells, including primordial germ cells, we conducted examination of expression patterns of developmental genes and histological observation. We also attempted the new experimental techniques for lineage tracing after introduction of artificial gene constructs. Comparison with insights from other vertebrate species implied the evolutionary relationships of the migratory undifferentiated precursor cells and the establishment of complex and diverse morphology of vertebrates.
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