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Identification of the transposases that contribute to the mobility of long-lived transposons.

Research Project

Project/Area Number 25440180
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Genetics/Chromosome dynamics
Research InstitutionHiroshima University

Principal Investigator

Hikosaka Akira  広島大学, 総合科学研究科, 准教授 (30263635)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywordsトランスポゾン / 転移酵素 / ツメガエル / 進化 / ゲノム
Outline of Final Research Achievements

I explored the transposases that contribute to the mobility of long-lived nonautonomous transposons, T2-A1 and T2-C, in the Western clawed frog Xenopus tropicalis. In that process, I created an in silico pipeline to analyze the evolution of transposases, and analyzed the evolution of transposases in X. tropicalis and X. laevis. In addition, I elucidated the dynamics of transposable elements in Xenopus evolution, especially in the allopolyploidization of X. laevis.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (4 results)

All 2015 2014 Other

All Journal Article (1 results) (of which Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (3 results)

  • [Journal Article] Distribution of the T2-MITE family transposons in the Xenopus (Silurana) tropicalis genome.2015

    • Author(s)
      Akira Hikosaka, Yoshinobu Uno, Yoichi Matsuda
    • Journal Title

      Cytogenetic and Genome Research

      Volume: in press Issue: 3-4 Pages: 230-242

    • DOI

      10.1159/000430764

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] ツメガエルにおけるDNA型トランスポゾンの進化2015

    • Author(s)
      彦坂暁
    • Organizer
      ツメガエル研究集会
    • Place of Presentation
      秋田県秋田市
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] Molecular domestication of transposons in Xenopus2014

    • Author(s)
      Akira Hikosaka
    • Organizer
      Frontiers in Amphibian Biology: Endangered Species Conservation and Genome Editing
    • Place of Presentation
      Hiroshima University, Hiroshima
    • Related Report
      2013 Research-status Report
  • [Presentation] ツメガエルKolobokトランスポゾンの転移酵素の進化

    • Author(s)
      彦坂暁
    • Organizer
      日本ツメガエル研究集会
    • Place of Presentation
      山口県秋吉台
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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