Evolvability of thermophilic proteins from archaea and bacteria
| Project/Area Number |
25440194
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Evolutionary biology
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| Research Institution | Kyoto Prefectural University |
|---|
Principal Investigator |
Takano Kazufumi 京都府立大学, 生命環境科学研究科(系), 教授 (40346185)
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|---|
| Project Period (FY) |
2013-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,330,000 (Direct Cost: ¥4,100,000、Indirect Cost: ¥1,230,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | タンパク質 / 進化 / 安定性 / 好熱菌 |
|---|
| Outline of Final Research Achievements |
To understand the evolution of life, we focused proteins. Proteins have changed their amino acid sequences along with evolution. In this study, we investigated a random mutational drift of proteins for evolution. Our results collectively support a crucial link between protein evolution and stabilization mechanisms based on the evolutionary history of organisms.
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Report
(4 results)
Research Products
(7 results)
