| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
Rice BSR1 is a dual-specificity protein kinase whose overexpression confers disease resistance against multiple pathogens. In this study, we have identified autophosphorylated tyrosine residues in BSR1. We have also mutated each tyrosine residues and examined the effects of mutations on kinase activity and tyrosine phosphorylation of BSR1. By overexpressing kinase-dead or tyrosine-replaced mutant bsr1, we have shown that kinase activity is essential for disease resistance and that tyrosine phosphorylation is important for full activity of BSR1 in disease resistance. We have also shown that SA signaling is dispensable for disease resistance conferred by BSR1.
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