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Screening of novel candidate compounds for next-generation herbicides and an investigation of their modes of action

Research Project

Project/Area Number 25450068
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Plant protection science
Research InstitutionUniversity of Tsukuba

Principal Investigator

SUNOHARA Yukari  筑波大学, 生命環境系, 講師 (00302539)

Co-Investigator(Kenkyū-buntansha) MATSUMOTO Hiroshi  筑波大学, 生命環境系, 教授 (10199888)
Research Collaborator BABA Yohei  
FUJIMURA Kaori  
NAKANO Kaori  
ITOH Mizuki  
NISHIMURA Akihiro  
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2013: ¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Keywordsアレロケミカル / 天然生理活性物質 / 植物成長抑制作用 / 除草剤 / 二次代謝産物 / 植物成育抑制作用 / 揮発性物質 / 活性酸素 / 新規除草剤候補物質 / 新規除草剤候補化合物 / アレロパシー
Outline of Final Research Achievements

Various medicinal, tropical, and subtropical plant species were screened for phytotoxic volatile compounds in order to find novel candidate compounds for next-generation herbicides, and the characterization of several promising compounds including eucarvone, hinokitiol, cumin aldehyde, and octyl acetate was investigated to understand their modes of action. Eucarvone, hinokitiol, cumin aldehyde, and octyl acetate, which have carbonyl function, induced overproduction of reactive oxygen species (ROS) and oxidative damage in the susceptible plant species. However, it was proposed that the effects of these compounds were brought about by different mechanisms.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (13 results)

All 2016 2015 2014 2013

All Journal Article (5 results) (of which Peer Reviewed: 5 results,  Acknowledgement Compliant: 1 results) Presentation (8 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Screening and identification of phytotoxic volatile compounds in medicinal plants and characterizations of a selected compound, eucarvone2015

    • Author(s)
      Sunohara, Y., Y. Baba, S. Matsuyama, K. Fujimura and H. Matsumoto
    • Journal Title

      Protoplasma

      Volume: 未定 Issue: 4 Pages: 1047-1059

    • DOI

      10.1007/s00709-014-0739-4

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Involvement of heme synthesis in growth stimulation of maize seedlings by 5-aminolevulinic acid2015

    • Author(s)
      Yonezawa, T., Y. Sunohara and H. Matsumoto
    • Journal Title

      Weed Biology and Management

      Volume: 15 Issue: 1 Pages: 53-60

    • DOI

      10.1111/wbm.12064

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] L-DOPA inhibited the root growth of lettuce by inducing reactive oxygen species generation2013

    • Author(s)
      Mushtaq, M. N., Y. Sunohara and H. Matsumoto
    • Journal Title

      Weed Biology and Management

      Volume: 13 Issue: 4 Pages: 129-134

    • DOI

      10.1111/wbm.12019

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Allelochemical L-DOPA induces quinoprotein adducts and inhibits NADH dehydrogenase activity and root growth of cucumber2013

    • Author(s)
      Mushtaq, M. N., Y. Sunohara and H. Matsumoto
    • Journal Title

      Plant Physiology and Biochemistry

      Volume: 70 Pages: 374-378

    • DOI

      10.1016/j.plaphy.2013.06.003

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Bioactive l-DOPA induced quinoprotein formation to inhibit root growth of cucumber seedlings2013

    • Author(s)
      Mushtaq, M. N., Y. Sunohara and H. Matsumoto
    • Journal Title

      Journal of Pesticide Science

      Volume: 38 Issue: 2 Pages: 68-73

    • DOI

      10.1584/jpestics.D13-005

    • NAID

      130004445306

    • ISSN
      1348-589X, 1349-0923
    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] ヒノキチオール処理によるイネ根部でのH2O2 蓄積への抗酸化酵素活性の関与2016

    • Author(s)
      伊藤瑞紀・春原由香里・岩上哲史・藤井義晴・松本 宏
    • Organizer
      日本雑草学会第55回大会
    • Place of Presentation
      東京農業大学世田谷キャンパス、東京都世田谷区
    • Year and Date
      2016-03-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] オクチルアセテートによる根部生育抑制作用における活性酸素発生の関与2016

    • Author(s)
      西村彰紘・春原由香里・松山 茂・岩上哲史・松本 宏
    • Organizer
      日本雑草学会第55回大会
    • Place of Presentation
      東京農業大学世田谷キャンパス、東京都世田谷区
    • Year and Date
      2016-03-29
    • Related Report
      2015 Annual Research Report
  • [Presentation] Determination and phytotoxic characterization of octyl acetate2015

    • Author(s)
      Akihiro Nishimura, Yukari Sunohara, Shigeru Matsuyam and Hiroshi Matsumoto
    • Organizer
      25th Asian-Pacific Weed Science Conference
    • Place of Presentation
      インド、ハイデラバード
    • Year and Date
      2015-10-13
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] クミンアルデヒド処理によるタマネギ根部での細胞分裂とプログラム細胞死誘導の検討2015

    • Author(s)
      春原由香里・中野 香・松本 宏
    • Organizer
      日本雑草学会第54回大会
    • Place of Presentation
      秋田・秋田県立大学
    • Year and Date
      2015-04-18 – 2015-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] オイカルボン処理によるネ根部でのシュウ酸化酵素活性、 H2O2含量 、 リグニン含量 への影響検討2015

    • Author(s)
      藤村香里 ・春原由香里・ 松本 宏
    • Organizer
      日本雑草学会第54回大会
    • Place of Presentation
      秋田・秋田県立大学
    • Year and Date
      2015-04-18 – 2015-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] ヒノキチオール処理によるイネ根部での変動タンパク質の解析と活性酸素発生誘導の検討2015

    • Author(s)
      伊藤瑞紀・春原由香里・小松節子・藤井義晴(農
    • Organizer
      日本雑草学会第54回大会
    • Place of Presentation
      秋田・秋田県立大学
    • Year and Date
      2015-04-18 – 2015-04-19
    • Related Report
      2014 Research-status Report
  • [Presentation] クミンから発生する揮発性物質クミンアルデヒドの生育抑制活性と活性酸素発生の検討2014

    • Author(s)
      中野香・春原由香里・松山茂・松本宏
    • Organizer
      日本雑草学会第53回大会
    • Place of Presentation
      東京・法政大学
    • Related Report
      2013 Research-status Report
  • [Presentation] オイカルボンと類縁化合物の作用性比較とオイカルボン処理により変動するイネタンパク質の解析2014

    • Author(s)
      藤村香里・春原由香里・小松節子・藤井義晴・松本宏
    • Organizer
      日本雑草学会第53回大会
    • Place of Presentation
      東京・法政大学
    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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