Evaluation of allergenicity of food proteins sensitized from dermal.
| Project/Area Number |
25450187
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Food science
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| Research Institution | Kinki University |
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Principal Investigator |
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | アレルギー / 経皮感作 / 食物アレルギー / 大豆 / 食物アレルゲン / 大豆タンパク質 / アレルゲン / IgE / IgG |
|---|
| Outline of Final Research Achievements |
Evaluation of allergenicity of food proteins sensitized from dermal was performed. The experimental system that food antigen invaded from skin was established using mice animal model. IgE antibody against subjected food protein was detected in serum. As food sample applied, soybean extract was applied to mouse skin using this established evaluation system, and it was considered an antibody to what kind of protein of soybeans was produced. As a result, an antibody was produced to the allergen of soybeans called Gly m5.
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Report
(4 results)
Research Products
(28 results)
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[Journal Article] Identification of peamaclein as a marker allergen related to systemic reactions in peach allergy,2014
Author(s)
Inomata N, Okazaki F, Moriyama T, Nomura Y, Yamaguchi Y, Honjoh T, Kawamura Y, Narita H, Aihara M
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Journal Title
Annals of Allergy, Asthma & Immunology
Volume: 112
Pages: 175-177
Related Report
Peer Reviewed
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[Presentation] Diversity of food allergy2015
Author(s)
Tatsuya Moriyama
Organizer
12th Asian Congress of Nutrition (ACN2015)
Place of Presentation
PACIFICO Yokohama, Kanagawa, Japan
Year and Date
2015-05-16
Related Report
Int'l Joint Research / Invited
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