| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2014: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Outline of Final Research Achievements |
The present study revealed that growth hormone-releasing hormone, which stimulates growth hormone release, inhibits feeding behavior in chicks. Although it is suggested that there would be several fragments of growth hormone-releasing hormone in chickens, the full-length of growth hormone-releasing hormone showed the strongest anorexigenic effect in chicks when administered centrally and peripherally. Growth hormone-releasing hormone did not induced behavioral changes and corticosterone release, suggesting that the anorexigenic effect would not be related to abnormal behavior and stress-related behavior. In addition, prolactin-releasing peptide, which inhibits growth hormone release, stimulated feeding behavior in chicks. These effects were completely different from the results of mammals. The present study revealed that growth hormone-releasing hormone and prolactin-releasing peptide are related to unique feeding regulatory mechanism of chicks.
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