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Risk analysis of emerging zoonotic viral diseases caused by recently identified bunyaviruses and rhabdoviruses

Research Project

Project/Area Number 25450438
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Veterinary medical science
Research InstitutionNational Institute of Infectious Diseases

Principal Investigator

MORIKAWA Shigeru  国立感染症研究所, 獣医科学部, 部長 (00167686)

Co-Investigator(Kenkyū-buntansha) 加来 義浩  国立感染症研究所, 獣医科学部, 主任研究官 (70392321)
Project Period (FY) 2013-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords人獣共通感染症 / 新興ウイルス感染症 / 動物由来ウイルス感染症 / 疫学 / SFTS virus / Bhanja virus / Oita virus / Heartland virus / Bas-Congo virus
Outline of Final Research Achievements

The risk of emerging virus infection as a zoonotic infection was evaluated in Japan. SFTSV was infected before 2005, so that SFTS, a first human case identified in Japan in 2013 was existed as unknown febrile illness. Bhanja virus, which is relatively related to SFTSV, was considered to be not immersed in the domestic virus yet in Japan. We found SFTS and Bhanja virus were serologically cross-reacted very little if any. The risk of Bhanja virus is considered to be very low in Japan. Domestic Oita virus and Fukuoka virus were differed genetically from Bas Congo virus by phylogenetic analysis and they did not cross-reacted each other serologically.

Report

(5 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (19 results)

All 2016 2015 2014

All Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Open Access: 1 results) Presentation (14 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] ペットとウイルス感染症2016

    • Author(s)
      森川 茂
    • Journal Title

      臨床とウイルス

      Volume: 44 Pages: 47-52

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 重症熱性血小板減少症候群2016

    • Author(s)
      森川 茂
    • Journal Title

      日本臨床

      Volume: 74 Pages: 1985-1991

    • NAID

      130004836758

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Epidemiological and pathological study of feline morbillivirus infection in domestic cats in Japan.2016

    • Author(s)
      Park ES, Suzuki M, Kimura M, Mizutani H, Saito R, Kubota N, Hasuike Y, Okajima J, Kasai H, Sato Y, Nakajima N, Maruyama K, Imaoka K, Morikawa S.
    • Journal Title

      BMC Vet Res.

      Volume: 12 Issue: 1 Pages: 228-228

    • DOI

      10.1186/s12917-016-0853-y

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] SFTS(重症熱性血小板減少症候群)2016

    • Author(s)
      森川 茂
    • Journal Title

      医学のあゆみ

      Volume: 別册 Pages: 42-48

    • Related Report
      2015 Research-status Report
  • [Journal Article] 重症熱性血小板減少症候群(SFTS)2015

    • Author(s)
      森川 茂
    • Journal Title

      Progress in Medicine

      Volume: 35 (12) Pages: 1907-1911

    • Related Report
      2015 Research-status Report
  • [Presentation] Current situation of SFTS in Japan2016

    • Author(s)
      Shigeru Morikawa
    • Organizer
      The 10th China-Japan-Korea Forum for Communicable Disease Control and Prevention
    • Place of Presentation
      北京
    • Year and Date
      2016-12-19
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ニホンジカより採取したマダニ類のSFTSウイルス遺伝子保有状況から見た自然界におけるSFTSウイルスの維持様式2016

    • Author(s)
      藤田修、宇田晶彦、木村昌伸、藤田博己、今岡浩一、森川茂
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] へニパウイルスC末端欠損F, G蛋白質を用いた効率的なシュードタイプVSVの作製2016

    • Author(s)
      加来義浩、朴ウンシル、野口章、今岡浩一、井上智、森川茂
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] Positive correlation between SFTS virus antibody positive rate in wild deer and number of SFTS patients2016

    • Author(s)
      Shigeru Morikawa, Masanobu Kimura, Tomoki Yoshikawa<SUP>1</SUP>, Yoshihiro Kaku, Eun-sil Park, Koichi Imaoka, Masayuki Saijo and Ken Maeda
    • Organizer
      第64回日本ウイルス学会学術集会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] モンゴルにおける動物のクリミア・コンゴ出血熱ウイルスの血清疫学2016

    • Author(s)
      森川茂、朴ウンシル、木村昌伸、福士秀悦、今岡浩一
    • Organizer
      第159回日本獣医学会
    • Place of Presentation
      神奈川
    • Year and Date
      2016-09-06
    • Related Report
      2016 Annual Research Report
  • [Presentation] フィリピンにおける2014年のニパウイルス感染症の流行2015

    • Author(s)
      Yoshihiro Kaku,Makoto Kuroda,Mariko Saito-Obata,Akira Noguchi,Akiko Okutani, Tsuyoshi Sekizuka,Satoshi Inoue,Shigeru Morikawa
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-22
    • Related Report
      2015 Research-status Report
  • [Presentation] Prevalence of severe fever with thrombocytopenia syndrome virus antibodies in wild Japanese deer2015

    • Author(s)
      Shigeru Morikawa,Masanobu Kimura,Yoshihiro Kaku,Park Eun Sil,Koich Imaoka, Masayuki Saijo,Ken Maed
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-22
    • Related Report
      2015 Research-status Report
  • [Presentation] Epidemiology of severe fever with thrombocytopenia syndrome virus in animals2015

    • Author(s)
      Ken Maeda,Chinami Hamasaki,Ryusei Kuwata,Kenzo Yonemitsu,Shohei Minami, Hiroshi Shimoda,Ai Takano,Kazuo Suzuki,Nobuyuki Shiranaga,Shigeru Morikawa
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-22
    • Related Report
      2015 Research-status Report
  • [Presentation] Establishment of highly susceptible C57BL/6J mice lacking the type I IFN receptor to SFTS virus infection2015

    • Author(s)
      Yuki Koyama,Park Eun-Sil,Tian Deyu,Akihiko Uda,Michio Suzuki,Tadaki Suzuki, Shigeru Morikawa
    • Organizer
      第63回日本ウイルス学会学術集会
    • Place of Presentation
      福岡
    • Year and Date
      2015-11-22
    • Related Report
      2015 Research-status Report
  • [Presentation] SFTS ウイルスの生活環における野生のシカの役割2014

    • Author(s)
      森川茂、朴 ウンシル、今岡 浩一、前田 健、宇田 晶彦
    • Organizer
      第62回日本ウイルス学会学術集会
    • Place of Presentation
      横浜市、神奈川
    • Year and Date
      2014-11-10 – 2014-11-12
    • Related Report
      2014 Research-status Report
  • [Presentation] 国内で分離された未分類のラブドウイルスの遺伝学的解析2014

    • Author(s)
      加来義浩、奥谷晶子、河合康洋、野口章、濱本紀子、梁瀬徹、加藤友子、新井智、井上智、森川茂
    • Organizer
      第157回日本獣医学会学術集会
    • Place of Presentation
      札幌市、北海道
    • Year and Date
      2014-09-09 – 2014-09-12
    • Related Report
      2014 Research-status Report
  • [Presentation] Severe fever with thrombocytopenia syndrome virus in animals and ticks in Japan.2014

    • Author(s)
      Shigeru Morikawa, Akihiko Uda, Masanobu Kimura, Kawabata, Hiroki, Shuetsu Fukushi, Aiko Fukuma, Yoshihiro Kaku, Unsil Paku, Hideki Tani, Tomoyuki Yoshikawa, Aya Niikura, Shuji Ando, Sawabe Kyoko, Hiromi Fujita, Koichi Imaoka, Masayuki Shimojima, Masayuki Saijo, Ken Maeda.
    • Organizer
      The 10th China-Japan International Conference of Virology
    • Place of Presentation
      Changchun, China
    • Year and Date
      2014-08-25 – 2014-08-28
    • Related Report
      2014 Research-status Report
  • [Presentation] Severe fever with thrombocytopenia syndrome virus in domestic and wild animals in Japan.2014

    • Author(s)
      Shigeru Morikawa, Masanobu Kimura, Shuetsu Fukushi, Aiko Fukuma Yoshihiro Kaku, Unsil Paku, Hideki Tani Tomoyuki Yoshikawa, Koichi Imaoka, Masayuki Shimojima, Masayuki Saijo, Ken Maeda.
    • Organizer
      XVIth International Congress of Virology
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2014-07-27 – 2014-08-01
    • Related Report
      2014 Research-status Report
  • [Presentation] Severe fever with thrombocytopenia syndrome virus in ticks in Japan.2014

    • Author(s)
      Akihiko Uda, Hiroki Kawabata, Shuetsu Fukushi, Yoshiharu Kaku, Masayuki Shimojima, Shuji Ando, Ken Maeda, Hiromi Fujita, Masayuki Saijo, Shigeru Morikawa, Tomoyuki Yoshikawa, Aya Niikura, Sawabe Kyoko
    • Organizer
      XVIth International Congress of Virology
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2014-07-27 – 2014-08-01
    • Related Report
      2014 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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