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Development of the stereocontrolled synthesis of the highly oxygenated steroids

Research Project

Project/Area Number 25460007
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Chemical pharmacy
Research InstitutionThe University of Tokyo

Principal Investigator

Urabe Daisuke  東京大学, 薬学研究科(研究院), 講師 (80503515)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
Keywords有機合成化学 / 天然物 / 生物活性物質 / 全合成 / 立体選択性 / ステロイド / 立体化学 / 立体選択的変換反応 / アルドール反応 / グリコシル化 / 生理活性物質 / ラジカル反応 / カップリング
Outline of Final Research Achievements

In this research project, we have established the strategy for the divergent synthesis of the highly oxygenated steroid compounds. The stereocontrolled synthesis of the core system of the steroid has been developed by the convergent radical coupling of the diverse AB-rings and the D-ring and the following stereoselective intramolecular aldol reaction. Based on the developed method, the total synthesis of complex natural product ouabagenin has been achieved. Furthermore, the intermediate towards toosendanine has been synthesized.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (74 results)

All 2016 2015 2014 2013 Other

All Journal Article (25 results) (of which Int'l Joint Research: 2 results,  Peer Reviewed: 24 results,  Acknowledgement Compliant: 8 results,  Open Access: 4 results) Presentation (46 results) (of which Int'l Joint Research: 7 results,  Invited: 8 results) Book (1 results) Remarks (2 results)

  • [Journal Article] Symmetry-Driven Strategy for the Assembly of the Core Tetracycle of (+)-Ryanodine: Synthetic Utility of a Cobalt-Catalyzed Olefin Oxidation and α-Alkoxy Bridgehead Radical Reaction2016

    • Author(s)
      M. Nagatomo, K. Hagiwara, K. Masuda, M. Koshimizu, T. Kawamata, Y. Matsui, D. Urabe, M. Inoue
    • Journal Title

      Chem. Eur. J.

      Volume: 22 Issue: 1 Pages: 222-229

    • DOI

      10.1002/chem.201503640

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Total Synthesis of Crotophorbolone2015

    • Author(s)
      Asaba, T.; Katoh, Y.; Urabe, D.; Inoue, M.
    • Journal Title

      Angew. Chem. Int. Ed.

      Volume: 54 Issue: 48 Pages: 14457-14461

    • DOI

      10.1002/anie.201509160

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Total synthesis of four stereoisomers of (5Z,8Z,10E,14Z)-12-hydroxy-17,18-epoxy-5,8,10,14-eicosatetraenoic acid and their anti-Inflammatory activities2015

    • Author(s)
      Goto, T.; Urabe, D.; Isobe, Y.; Arita, M.; Inoue, M.
    • Journal Title

      Tetrahedron

      Volume: 71 Issue: 43 Pages: 8320-8332

    • DOI

      10.1016/j.tet.2015.08.047

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Total synthesis of four stereoisomers of (4Z,7Z,10Z,12E,16Z,18E)-14,20-dihydroxy-4,7,10,12,16,18-docosahexaenoic acid and their anti-inflammatory activities.2015

    • Author(s)
      Goto T, Urabe D, Masuda K, Isobe Y, Arita M, Inoue M.
    • Journal Title

      J Org Chem

      Volume: 80 Issue: 15 Pages: 7713-7726

    • DOI

      10.1021/acs.joc.5b01461

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] A Convergent Total Synthesis of Ouabagenin2015

    • Author(s)
      Ken Mukai, Satoshi Kasuya, Yuki Nakagawa, Daisuke Urabe, Masayuki Inoue
    • Journal Title

      Chemical Science

      Volume: 印刷中 Issue: 6 Pages: 3383-3387

    • DOI

      10.1039/c5sc00212e

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] N-(2,3,4,5,6-Pentafluorophenyl)maleimide as a Powerful Dienophile in Dearomatizing Diels-Alder Reactions2015

    • Author(s)
      K. Hagiwara, M. Iwatsu, D. Urabe, M. Inoue
    • Journal Title

      Heterocycles

      Volume: 90 Issue: 1 Pages: 659-672

    • DOI

      10.3987/com-14-s(k)23

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Asymmetric Total Synthesis of (−)-4-Hydroxyzinowol, a Highly Oxygenated Dihydro-β-Agarofuran2015

    • Author(s)
      Urabe, D.; Todoroki, H.; Inoue, M.
    • Journal Title

      Journal of Synthetic Organic Chemistry, Japan

      Volume: 73 Issue: 11 Pages: 1081-1091

    • DOI

      10.5059/yukigoseikyokaishi.73.1081

    • NAID

      130005113516

    • ISSN
      0037-9980, 1883-6526
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Radical-Mediated Three-Component Reaction: A Study toward the Total Synthesis of Resiniferatoxin2015

    • Author(s)
      Urabe, D.
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 63 Issue: 8 Pages: 565-572

    • DOI

      10.1248/cpb.c15-00373

    • NAID

      130005090108

    • ISSN
      0009-2363, 1347-5223
    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Multifunctionality of the N-Trichloroacetyl Group Developed in the Synthesis of Tetrodotoxin, a Puffer Fish Toxin2015

    • Author(s)
      Toshio Nishikawa, Daisuke Urabe, Masaatsu Adachi, Minoru Isobe
    • Journal Title

      Synlett

      Volume: 26 Issue: 14 Pages: 1930-1939

    • DOI

      10.1055/s-0034-1380781

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Convergent strategies in total syntheses of complex terpenoids2015

    • Author(s)
      Urabe, D.; Asaba, T.; Inoue, M.
    • Journal Title

      Chem. Rev.

      Volume: 115 Issue: 17 Pages: 9207-9231

    • DOI

      10.1021/cr500716f

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 合成化学者の特権!? 新規抗炎症性脂質メディエーターの発見2015

    • Author(s)
      占部大介
    • Journal Title

      ファルマシア

      Volume: 51 Pages: 800-800

    • NAID

      130007448246

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Total Synthesis of (-)-4-Hydroxyzinowol2014

    • Author(s)
      H. Todoroki, M. Iwatsu, D. Urabe, M. Inoue
    • Journal Title

      J. Org. Chem.

      Volume: 79 Issue: 18 Pages: 8835-8849

    • DOI

      10.1021/jo501666x

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Total Synthesis of Ryanodol2014

    • Author(s)
      Masanori Nagatomo, Masaki Koshimizu, Kengo Masuda, Toshiki Tabuchi, Daisuke Urabe, Masayuki Inoue
    • Journal Title

      Journal of the American Chemical Society

      Volume: 136 Issue: 16 Pages: 5916-5919

    • DOI

      10.1021/ja502770n

    • Related Report
      2014 Research-status Report 2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Studies in symmetry-driven synthesis of ryanodol: application of nucleophilic alkynylation for regio- and stereoselective desymmetrization2014

    • Author(s)
      K. Hagiwara, D. Urabe, M. Inoue
    • Journal Title

      Tetrahedron Lett.

      Volume: 55 Issue: 28 Pages: 3817-3819

    • DOI

      10.1016/j.tetlet.2014.05.075

    • Related Report
      2014 Research-status Report
    • Peer Reviewed
  • [Journal Article] Identification of 14,22014

    • Author(s)
      Yoshiyuki Yokokura, Yosuke Isobe, Shinnosuke Matsueda, Ryo Iwamoto, Tomomi Goto, Takeshi Yoshioka, Daisuke Urabe, Masayuki Inoue, Hiroyuki Arai and Makoto Arita
    • Journal Title

      the journal of biochemistry

      Volume: 156 Issue: 6 Pages: 315

    • DOI

      10.1093/jb/mvu044

    • Related Report
      2014 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] レペニンの全合成2014

    • Author(s)
      占部大介
    • Journal Title

      月刊化学

      Volume: 69 Pages: 61-62

    • Related Report
      2014 Research-status Report
  • [Journal Article] Eicosapentaenoic acid is converted via ω-3 epoxygenation to the anti-inflammatory metabolite 12-hydroxy-17,18-epoxyeicosatetraenoic acid2013

    • Author(s)
      Kubota T, Arita M, Isobe Y, Iwamoto R, Goto T, Yoshioka T, Urabe D, Inoue M, Arai H
    • Journal Title

      FASEB J.

      Volume: 28 Issue: 2 Pages: 586

    • DOI

      10.1096/fj.13-236224

    • Related Report
      2014 Research-status Report 2013 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] Et3B‐Mediated Radical-Polar Crossover Reaction for Single-Step Coupling of O,Te-Acetal, α,β-Unsaturated Ketones, and Aldehydes/Ketones2013

    • Author(s)
      Kamimura, D.; Urabe, D.; Nagatomo, M.; Inoue, M.
    • Journal Title

      Organic Letters

      Volume: 15 Issue: 19 Pages: 5122-5125

    • DOI

      10.1021/ol402563v

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Preparation and palladium-mediated cross-coupling of --benzoyloxyalkylzinc bromides2013

    • Author(s)
      Sakata, K.; Urabe, D.; Inoue, M
    • Journal Title

      Tetrahedron Letters

      Volume: (in press) Issue: 32 Pages: 4189-4192

    • DOI

      10.1016/j.tetlet.2013.05.114

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Concise Synthesis of the Multiply Oxygenated ABC-Ring System of the Dihydro-β-agarofurans2013

    • Author(s)
      Ishiyama, T.; Urabe, D.; Fujisawa, H.; Inoue, M.
    • Journal Title

      Organic Letters

      Volume: 15 Issue: 17 Pages: 4488-4491

    • DOI

      10.1021/ol402038b

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A convergent total synthesis of19-hydroxysarmentogenin.2013

    • Author(s)
      Mukai, K.; Urabe, D.; Kasuya, S.; Aoki, N.; Inoue, M
    • Journal Title

      Angewandte Chemie International Edition

      Volume: 52 Issue: 20 Pages: 5300-5304

    • DOI

      10.1002/anie.201302067

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] A radical-based approach for the construction of the tetracyclic structure of resiniferatoxin2013

    • Author(s)
      Murai, K.; Katoh, S.; Urabe, D.; Inoue, M
    • Journal Title

      Chemical Science

      Volume: 4 Issue: 6 Pages: 2364-2368

    • DOI

      10.1039/c3sc50329a

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Asymmetric synthesis of a highly functionalized bicyclo[3.2.2]nonene derivative.2013

    • Author(s)
      Tabuchi, T.; Urabe, D.; Inoue, M.
    • Journal Title

      Beilstein Journal of Organic Chemistry

      Volume: 9 Pages: 655-663

    • DOI

      10.3762/bjoc.9.74

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Symmetry-driven synthesis of 9-demethyl-10,15-dideoxyryanodol.2013

    • Author(s)
      Urabe, D.; Nagatomo, M.; Hagiwara, K.; Masuda, K.; Inoue, M.
    • Journal Title

      Chemical Science

      Volume: 4 Issue: 4 Pages: 1615-1619

    • DOI

      10.1039/c3sc00023k

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Stereochemical assignment and anti-inflammatory properties of the omega-3 lipid mediator resolvin E32013

    • Author(s)
      Y Isobe, M. Arita, R. Iwamoto, D. Urabe, H. Todoroki, K. Masuda, M. Inoue and H. Arai
    • Journal Title

      The Journal of Biochemistry

      Volume: 153 Issue: 4 Pages: 355

    • DOI

      10.1093/jb/mvs151

    • NAID

      40019622680

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] ラジカル反応を基盤としたチグリアン・ダフナンジテルペン類の合成戦略2016

    • Author(s)
      占部大介
    • Organizer
      日本薬学会第136年会シンポジウム 天然物ケミカルバイオロジー(4):天然物合成とケミカルバイオロジー
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-29
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] タラチサミンの合成研究2016

    • Author(s)
      鎌倉大貴、轟木秀憲、占部大介、井上将行
    • Organizer
      日本薬学会 第136年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 高酸化度アガロフラン型セスキテルペンの全合成研究2016

    • Author(s)
      藤澤博基、占部大介、井上将行
    • Organizer
      日本薬学会 第136年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] ラジカル-極性交差反応を鍵としたC19ジテルペンアルカロイドの合成研究2016

    • Author(s)
      皆川功亮、占部大介、井上将行
    • Organizer
      日本薬学会 第136年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] チグリアン・ダフナンジテルペンの網羅的全合成研究2016

    • Author(s)
      浅羽太郎、占部大介、井上将行
    • Organizer
      日本薬学会 第136年会
    • Place of Presentation
      パシフィコ横浜、横浜
    • Year and Date
      2016-03-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] Unified total synthesis of oxygenated cardenolides2015

    • Author(s)
      Urabe, D.; Inoue, M.
    • Organizer
      PACIFICEHM2015
    • Place of Presentation
      Honolulu, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synthetic Study of Puberuline C2015

    • Author(s)
      Hagiwara, K.; Tabuchi, T.; Urabe, D.; Inoue, M.
    • Organizer
      Cambridge-Utokyo joint symposium
    • Place of Presentation
      Cambridge, England
    • Year and Date
      2015-11-23
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Total Synthesis of Crotophorbolone2015

    • Author(s)
      Urabe, D.; Inoue, M.
    • Organizer
      the 15th Tateshina Conference on Organic Chemistry
    • Place of Presentation
      Chino, Japan
    • Year and Date
      2015-11-08
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synthetic Study of Batrachotoxin2015

    • Author(s)
      Sakata, K.; Wang, Y.; Urabe, D.; Inoue, M.
    • Organizer
      ICCEOCA-10
    • Place of Presentation
      Kaohsiung, Taiwan
    • Year and Date
      2015-11-02
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synthetic Study of Batrachotoxin2015

    • Author(s)
      Sakata, K.; Wang, Y.; Urabe, D.; Inoue, M.
    • Organizer
      Junior ICCEOCA-5
    • Place of Presentation
      Taipei, China
    • Year and Date
      2015-10-30
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Synthetic Study of Highly Oxygenated Agarofuran Sesquiterpenoid2015

    • Author(s)
      Fujisawa, H.; Ishiyama, T.; Urabe, D.; Inoue, M.
    • Organizer
      LMU-UTOKYO SYMPOSIUM 2015
    • Place of Presentation
      Munich, German
    • Year and Date
      2015-10-27
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] レジニフェラトキシンの全合成研究2015

    • Author(s)
      橋本 哲、加藤駿一郎、村井耕一、占部大介、井上将行
    • Organizer
      第41回反応と合成の進歩シンポジウム
    • Place of Presentation
      近畿大学、東大阪
    • Year and Date
      2015-10-26
    • Related Report
      2015 Annual Research Report
  • [Presentation] 高酸化度アガロフラン型セスキテルペンの全合成研究2015

    • Author(s)
      藤澤博基、石山備凡、占部大介、井上将行
    • Organizer
      第32回有機合成化学セミナー
    • Place of Presentation
      ニューウェルシティ湯河原、熱海
    • Year and Date
      2015-09-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] 抗炎症性脂質メディエーターの全合成2015

    • Author(s)
      占部大介,
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー~分子標的と活性制御~」地区ミニシンポジウム・仙台「ケミカルバイオロジーにおける天然物」
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2015-06-30
    • Related Report
      2015 Annual Research Report
    • Invited
  • [Presentation] チグリアン/ダフナンジテルペン類の合成戦略:クロトホルボロンの全合成2015

    • Author(s)
      占部大介
    • Organizer
      新学術領域研究「天然物ケミカルバイオロジー~分子標的と活性制御~」第8回公開シンポジウム
    • Place of Presentation
      東北大学、仙台
    • Year and Date
      2015-06-08
    • Related Report
      2015 Annual Research Report
  • [Presentation] Synthetic Study of Resiniferatoxin2015

    • Author(s)
      Kato, S.; Murai, K.; Urabe, D.; Inoue, M.
    • Organizer
      RSC Organic Chemistry Symposia
    • Place of Presentation
      東京大学、東京
    • Year and Date
      2015-06-03
    • Related Report
      2015 Annual Research Report
    • Int'l Joint Research
  • [Presentation] プベルリンCの全合成研究2015

    • Author(s)
      萩原浩一、田渕俊樹、占部大介、井上将行
    • Organizer
      第13回次世代を担う有機化学シンポジウム
    • Place of Presentation
      立命館大学、大津
    • Year and Date
      2015-05-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] 橋頭位ラジカルを用いたC19ジテルペンアルカロイドの合成研究2015

    • Author(s)
      皆川功亮、山下智也、田渕俊樹、占部大介、井上将行
    • Organizer
      第69回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      横浜国立大学、横浜
    • Year and Date
      2015-05-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] ラジカル反応を基盤とした複雑天然物の全合成研究2015

    • Author(s)
      占部大介
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫
    • Year and Date
      2015-03-25 – 2015-03-28
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] プベルリンCの合成研究2015

    • Author(s)
      萩原浩一、田渕俊樹、占部大介、井上将行
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫
    • Year and Date
      2015-03-25 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] タラチサミンの全合成研究2015

    • Author(s)
      轟木秀憲、鎌倉大貴、占部大介、井上将行
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫
    • Year and Date
      2015-03-25 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] レジニフェラトキシンの全合成研究2015

    • Author(s)
      橋本哲、加藤駿一郎、村井耕一、占部大介、井上将行
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫
    • Year and Date
      2015-03-25 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 高酸化度アガロフランセスキテルペンの全合成研究2015

    • Author(s)
      藤澤博基、石山備凡、占部大介、井上将行
    • Organizer
      日本薬学会第135年会
    • Place of Presentation
      兵庫
    • Year and Date
      2015-03-25 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] Total synthesis of crotophorbolone2014

    • Author(s)
      Taro Asaba, Yuki Katoh, Daisuke Urabe, Masayuki Inoue
    • Organizer
      JICCEOCA-4 and ICCEOCA-9/NICCEOCA-5
    • Place of Presentation
      bangkok, thailand/Kuala Lumpur, Malaysia
    • Year and Date
      2014-11-25 – 2014-12-08
    • Related Report
      2014 Research-status Report
  • [Presentation] クロトホルボロンの全合成2014

    • Author(s)
      浅羽太郎、嘉藤裕樹、占部大介、井上将行
    • Organizer
      第40回反応と合成の進歩シンポジウム
    • Place of Presentation
      宮城
    • Year and Date
      2014-11-10 – 2014-11-11
    • Related Report
      2014 Research-status Report
  • [Presentation] 高酸化度アガロフラン型セスキテルペンの全合成研究2014

    • Author(s)
      藤澤博基、石山備凡、占部大介、井上将行
    • Organizer
      第106回有機合成シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-11-06 – 2014-11-07
    • Related Report
      2014 Research-status Report
  • [Presentation] A Unified Approach to the Cardenolides and Bufadienolides: Total Synthesis of Ouabagenin2014

    • Author(s)
      Daisuke Urabe
    • Organizer
      The 3rd International Symposium on Chemical Biology of Natural Products: Target ID and Regulation of Bioactivity
    • Place of Presentation
      Osaka
    • Year and Date
      2014-10-28 – 2014-10-29
    • Related Report
      2014 Research-status Report
  • [Presentation] (+)-リアノジンの不斉全合成2014

    • Author(s)
      枡田健吾、長友優典、小清水正樹、萩原幸司、田渕俊樹、占部大介、井上将行
    • Organizer
      第56回天然有機化合物討論会
    • Place of Presentation
      高知
    • Year and Date
      2014-10-15 – 2014-10-17
    • Related Report
      2014 Research-status Report
  • [Presentation] 橋頭位ラジカルを用いた高酸化度テルぺノイドの全合成研究2014

    • Author(s)
      占部大介
    • Organizer
      明治薬科大学
    • Place of Presentation
      東京
    • Year and Date
      2014-09-26
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] リアノドールの全合成2014

    • Author(s)
      小清水正樹、長友優典、枡田健吾、萩原幸司、田渕俊樹,占部大介、井上将行
    • Organizer
      第31回有機合成化学セミナー
    • Place of Presentation
      福岡
    • Year and Date
      2014-09-17 – 2014-09-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 橋頭位ラジカルを用いた高酸化度テルぺノイドの全合成研究2014

    • Author(s)
      占部大介
    • Organizer
      第49回天然物化学談話会
    • Place of Presentation
      岡山
    • Year and Date
      2014-07-02 – 2014-07-04
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] プベルリンCの合成研究2014

    • Author(s)
      萩原浩一、田渕俊樹、占部大介、井上将行
    • Organizer
      第105回有機合成シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-06-10 – 2014-06-11
    • Related Report
      2014 Research-status Report
  • [Presentation] リアノドールの全合成2014

    • Author(s)
      小清水正樹、長友優典,枡田健吾、田渕俊樹,占部大介,井上将行
    • Organizer
      第12回次世代を担う有機化学シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2014-05-23 – 2014-05-24
    • Related Report
      2014 Research-status Report
  • [Presentation] Total Synthesis of 19-Hydroxysarmentogenin2014

    • Author(s)
      Daisuke Urabe, Masayuki Inoue
    • Organizer
      International Startup Symposium of Cutting-Edge Organic Chemistry in Asia (III)
    • Place of Presentation
      Hsinchu, Taiwan
    • Year and Date
      2014-04-19 – 2014-04-22
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] ウアバゲニンの全合成2014

    • Author(s)
      占部大介
    • Organizer
      日本薬学会第134年会シンポジウム有機合成の若い力
    • Place of Presentation
      熊本県、熊本市
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] クロトホルボロンの全合成研究2014

    • Author(s)
      浅羽太郎、嘉藤裕樹、占部大介、井上将行
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県、熊本市
    • Related Report
      2013 Research-status Report
  • [Presentation] バトラコトキシンの全合成研究2014

    • Author(s)
      坂田光命、占部大介、井上将行
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県、熊本市
    • Related Report
      2013 Research-status Report
  • [Presentation] プベルリンCの合成研究2014

    • Author(s)
      萩原浩一、田渕俊樹、占部大介、井上将行
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県、熊本市
    • Related Report
      2013 Research-status Report
  • [Presentation] レジニフェラトキシンの全合成研究2014

    • Author(s)
      加藤駿一郎、村井耕一、占部大介、井上将行
    • Organizer
      日本薬学会第134年会
    • Place of Presentation
      熊本県、熊本市
    • Related Report
      2013 Research-status Report
  • [Presentation] ラジカル反応を鍵とした高酸化度テルペノイドの全合成研究2013

    • Author(s)
      占部大介
    • Organizer
      第1回慶應有機化学若手シンポジウム
    • Place of Presentation
      神奈川県、横浜市
    • Related Report
      2013 Research-status Report
    • Invited
  • [Presentation] セラングリンの合成研究2013

    • Author(s)
      藤澤博基、石山備凡、占部大介、井上将行
    • Organizer
      第57回日本薬学会関東支部大会
    • Place of Presentation
      東京都、板橋区
    • Related Report
      2013 Research-status Report
  • [Presentation] 立体選択的な高酸化度ステロイド骨格構築法の開発2013

    • Author(s)
      中川雄喜、青木直人、占部大介、井上将行
    • Organizer
      第65回有機合成化学協会関東支部シンポジウム
    • Place of Presentation
      新潟県、新潟市
    • Related Report
      2013 Research-status Report
  • [Presentation] Synthetic study of 4-hydroxyzinowol2013

    • Author(s)
      Todoroki, H.; Iwatsu, M.; Masuda, K.; Urabe, D.; Inoue, M.
    • Organizer
      3rd Junior International Conference on Cutting-Edge Organic Chemistry in Asia
    • Place of Presentation
      千葉県、千葉市
    • Related Report
      2013 Research-status Report
  • [Presentation] Synthetic study of 4-hydroxyzinowol2013

    • Author(s)
      Todoroki, H.; Iwatsu, M.; Masuda, K.; Urabe, D.; Inoue, M.
    • Organizer
      The 8th International Conference on Cutting-Edge Organic Chemistry in Asia and The 4th New Phase International Conference on Cutting-Edge Organic Chemistry in Asia
    • Place of Presentation
      大阪府、大阪市
    • Related Report
      2013 Research-status Report
  • [Presentation] 4-ヒドロキシジノウォールの合成研究2013

    • Author(s)
      轟木秀憲、岩津理史、枡田健吾、占部大介、井上将行
    • Organizer
      第55回天然有機化合物討論会
    • Place of Presentation
      京都府、京都市
    • Related Report
      2013 Research-status Report
  • [Presentation] タラチサミンの全合成研究2013

    • Author(s)
      田渕俊樹、占部大介、井上将行
    • Organizer
      第39回反応と合成の進歩シンポジウム
    • Place of Presentation
      福岡県、福岡市
    • Related Report
      2013 Research-status Report
  • [Book] Strategy and Tactics in Organic Synthesis Vol.92013

    • Author(s)
      Inoue, M.; Urabe, D.
    • Total Pages
      322
    • Publisher
      elsevier
    • Related Report
      2013 Research-status Report
  • [Remarks] 東京大学大学院薬学系研究科有機反応化学教室

    • URL

      http://www.f.u-tokyo.ac.jp/~inoue/

    • Related Report
      2015 Annual Research Report
  • [Remarks] 東京大学大学院薬学系研究科有機反応化学教室 Inoue Research Group

    • URL

      http://www.f.u-tokyo.ac.jp/~inoue/

    • Related Report
      2013 Research-status Report

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Published: 2014-07-25   Modified: 2019-07-29  

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