Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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Outline of Final Research Achievements |
The development of an efficient synthetic method for nitrogen-containing heterocyclic compounds is highly important, because they are contained in a large number of biologically active compounds. In this research, we conducted the study on the rearrangement reaction of haloamines (nitrogen-halogen compounds), an electrophilic nitrogen source, to develop a new synthesis method for nitrogen-containing compounds. As a results, we have found that the rearrangement reactions of haloamines having electron-donating groups such as a nitrogen atom, an oxygen atom, and aromatic substituents occur efficiently and shown their usefulness for the heterocyclic synthesis.
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