Asymmetric synthesis of helicenes by selective cycloaddition reactions of benzynes
Project/Area Number |
25460018
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Chemical pharmacy
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Research Institution | Osaka University |
Principal Investigator |
IKAWA TAKASHI 大阪大学, 薬学研究科(研究院), 助教 (20453061)
|
Project Period (FY) |
2013-04-01 – 2016-03-31
|
Project Status |
Completed (Fiscal Year 2015)
|
Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
|
Keywords | ベンザイン / ヘリセン / ノナフラート / 多環式芳香族化合物 / 連続反応 / フラン / 環化付加反応 / らせん / アライン / シリル基 / 不斉合成 / 位置選択性 / ベンズジイン等価体 |
Outline of Final Research Achievements |
Many scientists are now interested in helicenes, which is multiply fused benzenes at ortho positions, and they are working on various advanced researches using helicenes. However, it is still challenging to synthesize functionalized helicenes in short steps. In this research, the development of novel synthesis of helicenes using benzynes has been achieved. Additionally, novel helical molecules were successfully synthesized through new reaction using fused benzynes.
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Report
(4 results)
Research Products
(64 results)
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[Journal Article] Development of a Highly Efficient Single-Mode Microwave Applicator with a Resonant Cavity and its Application to Continuous Flow Syntheses2015
Author(s)
Yokozawa, Saori; Ohneda, Noriyuki; Muramatsu, Ken; Okamoto, Tadashi; Odajima, Hiromichi; Ikawa, Takashi; Sugiyama, Jun-ichi; Fujita, Masashi; Sawairi, Taira; Egami, Hiromichi; Hamashima, Yoshitaka; Egi, Masahiro; Akai, Shuji
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Journal Title
RSC Adv.
Volume: 5
Issue: 14
Pages: 10204-10210
DOI
Related Report
Peer Reviewed
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[Journal Article] Generation of 3-Borylbenzynes, Their Regioselective Diels-Alder Reactions, and Theoretical Analysis2013
Author(s)
Takashi Ikawa, Akira Takagi, Yurio Kurita, Kozumo Saito, Kenji Azechi, Masahiro Egi, Yuji Itoh, Hiroaki Tkiwa, Yasuyuki Kita, and Shuji Akai
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Journal Title
Tetrahedron
Volume: 69
Issue: 21
Pages: 4338-4352
DOI
Related Report
Peer Reviewed
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[Book] 薬事日報2015
Author(s)
井川貴詞、赤井周司
Total Pages
1
Publisher
薬事日報社
Related Report
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