Research of spiroborate supramolecular polymer directing to medical materials

• Project/Area Number: 25460029
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Chemical pharmacy
• Research Institution: Tokushima Bunri University
• Principal Investigator: KAWAHATA Masatoshi 徳島文理大学, 薬学部, 助教 (00441593)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000); Fiscal Year 2013: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
• Keywords: 超分子 / スピロボラート / 単結晶X線構造解析 / シクロファン / アニオン性化合物 / ホストゲスト / ホスト―ゲスト

Outline of Final Research Achievements

Development and evaluation of supramolecular polymer using molecular techniques of spiroborates were achieved.
Spiroborates molecule as supramolecular polymer succeeded in the formation of supramolecular complexes with lanthanoid metals. The new macrocyclic spiroborates were successfully inclusion of cation molecules (viologen derivatives containing naphthalene therein) in its internal space. In addition, the structures of the macrocyclic spiroborates consisting multilayer were confirmed by single crystal X-ray structure analysis.

Research Products

• [Journal Article] Formation of Lanthanide(III)-containing Metallosupramolecular Arrays Induced by Tris(spiroborate) Twin Bowl (2015)
  • Author(s): H. Danjo, T. Nakagawa, . Katagiri, M. Kawahata, S. Yoshigai, T. Miyazawa, K. Yamaguchi
  • Journal Title: Cryst. Growth Des. Volume: 15 Issue: 1 Pages: 384-389
  • DOI: 10.1021/cg5014686
  • Peer Reviewed
• [Journal Article] Nestable Tetrakis(spiroborate) Nanocycles (2015)
  • Author(s): Hiroshi Danjo, Yuhki Hashimoto, Yuki Kidena, Ayumi Nogamine, Kosuke Katagiri, Masatoshi Kawahata, Toshifumi Miyazawa, Kentaro Yamaguchi
  • Journal Title: Org. Lett. Volume: 17 Issue: 9 Pages: 2154-2157
  • DOI: 10.1021/acs.orglett.5b00747
  • Peer Reviewed
• [Journal Article] Multilayered Inclusion Nanocycles of Anionic Spiroborates (2015)
  • Author(s): Hiroshi Danjo, Yuki Kidena, Masatoshi Kawahata, Hiroyasu Sato, Kosuke Katagiri, Toshifumi Miyazawa, Kentaro Yamaguchi
  • Journal Title: Org. Lett. Volume: 17 Issue: 07 Pages: 2466-2469
  • DOI: 10.1055/s-0034-1380955
  • Peer Reviewed
• [Journal Article] Multilayered Inclusion Nanocycles of Anionic Spiroborates (2015)
  • Author(s): H. Danjo, Y. Kidena, M. Kawahata, H. Sato, K. Katagiri, T. Miyazawa, K. Yamaguchi
  • Journal Title: Org. Lett. Volume: * Issue: 10 Pages: 2466-2469
  • DOI: 10.1021/acs.orglett.5b00974
  • Peer Reviewed
• [Journal Article] Preparation of Tris(spiroorthocarbonate) Cyclophanes as Back to Back Ditopic Hosts (2013)
  • Author(s): Hiroshi Danjo, Kazuhisa Iwaso, Masatoshi Kawahata, Kazuaki Ohara, Toshifumi Miyazawa, Kentaro Yamaguchi
  • Journal Title: Org. Lett. Volume: 15 Issue: 9 Pages: 2164-2167
  • DOI: 10.1021/ol4006882
  • Peer Reviewed
• [Presentation] スピロボラート型中空分子を用いたn積層構造の構築 (2016)
  • Author(s): 楠本一樹、橋本祐希、貴傳名祐希、片桐幸輔、川幡正俊、檀上博史、山口健太郎
  • Organizer: 日本化学会第９６春季年会
  • Place of Presentation: 京都
  • Year and Date: 2016-03-24
• [Presentation] 水素結合能を有する環状スピロボラートを利用した超分子ポリマーの創製 (2016)
  • Author(s): 仲谷瑞貴、川西裕子、片桐幸輔、川幡正俊、檀上博史、山口健太郎
  • Organizer: 日本化学会第９６春季年会
  • Place of Presentation: 京都
  • Year and Date: 2016-03-24
• [Presentation] 固有な空孔を有するスピロボラート型ホストの創製と分子認識挙動評価 (2016)
  • Author(s): 北居貴史、松本智博、増田勇貴、片桐幸輔、川幡正俊、檀上博史、山口健太郎
  • Organizer: 日本化学会第９６春季年会
  • Place of Presentation: 京都
  • Year and Date: 2016-03-24
• [Presentation] アミド基を導入した環状スピロボラート型分子接合素子の調製と連鎖会合能評価 (2015)
  • Author(s): 仲谷瑞貴・川西裕子・檀上博史・片桐幸輔・宮澤敏文・川幡正俊・山口健太郎
  • Organizer: 日本化学会第95春季年会
  • Place of Presentation: 日本大学理工学部船橋キャンパス／薬学部
  • Year and Date: 2015-03-26 – 2015-03-29
• [Presentation] スピロボラート・ナノサイクル・ナノケージ・アニオン性ホスト・超分子 (2015)
  • Author(s): 貴傳名祐希・野ヶ峯亜由美・増田勇貴・檀上博史・片桐幸輔・宮澤敏文・川幡正俊・山口健太郎
  • Organizer: 日本化学会第95春季年会
  • Place of Presentation: 日本大学理工学部船橋キャンパス／薬学部
  • Year and Date: 2015-03-26 – 2015-03-29
• [Presentation] テトラピリジニウム型カチオンナノサイクルの調製 (2015)
  • Author(s): 木谷和弘・檀上博史・片桐幸輔・宮澤敏文・川幡正俊・山口健太郎
  • Organizer: 日本化学会第95春季年会
  • Place of Presentation: 日本大学理工学部船橋キャンパス／薬学部
  • Year and Date: 2015-03-26 – 2015-03-29