| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
Mitochondrial outer membrane is highly permeable for various metabolites and ions. This high permeability is conferred by the voltage dependent anion channel expressed in the outer mitochondrial membrane. The carnitine palmitoyltransferase also present in the mitochondrial outer membrane is also responsible for the translocation of the fatty acids across mitochondrial membranes. In the present study, we focused on these two proteins, and tried to understand their structural and functional properties. These approaches are effective for better understanding of the properties of the mitochondrial outer membrane.
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