Screening for antiviral compounds targeting nuclear export system from natural resources
Project/Area Number |
25460125
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Natural medicines
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Research Institution | Nagasaki University |
Principal Investigator |
WATANABE Ken 長崎大学, 医歯薬学総合研究科(医学系), 助教 (00346909)
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Project Period (FY) |
2013-04-01 – 2017-03-31
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Project Status |
Completed (Fiscal Year 2016)
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Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
Keywords | インフルエンザウイルス / 阻害剤 / 抗ウイルス薬 / 核外輸送 / NP / 天然資源 / ウイルス / スクリーニング |
Outline of Final Research Achievements |
Objective of this study is to find novel anti-viral drugs especially anti-influenza viral drugs. Using cell culture and live virus system, we elucidated anti-viral activity of various natural products and chemicals. As a result, we found that many natural products such as food and plant extracts have anti-influenza viral activity with various mechanisms of action.These compounds and extracts may be useful for the development of novel anti viral drugs.
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Report
(5 results)
Research Products
(14 results)
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[Presentation] Drug discovery for influenza virus2016
Author(s)
4.Juliann Nzembi Makau, Ken Watanabe, Takeshi Ishikawa, Tsuyoshi Hamada, Nobuyuki Kobayashi, Noriyuki Nishida
Organizer
The 3rd International Symposium for the Promotion of Science and Technology Innovation Cooperation between Africa and Japan
Place of Presentation
JICA市ヶ谷ビル(東京都新宿区)
Year and Date
2016-07-13
Related Report
Int'l Joint Research
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