| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2013: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Outline of Final Research Achievements |
In this investigation, we screened Japanese Adverse Event Report (JADER) database. In addition, mechanism to induce adverse events was examined using in vitro experimental methods. At first, data files disclosed from PMDA was reconstructed to the relational database with File Maker or Microsoft Access. Based on these reconstructed databases, respective adverse events were extracted. It was found that some characteristics of patients were correlated with prognoses of adverse events. In addition, toxicities of the drugs were examined with cultured cells.
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