Maturation and degeneration of oocyte compared with neuronal degeneration.
| Project/Area Number |
25460256
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
General anatomy (including histology/embryology)
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| Research Institution | St. Marianna University School of Medicine |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
石塚 文平 聖マリアンナ医科大学, 医学部, 名誉教授 (80097336)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 卵巣 / 卵成熟 / 卵変性 / 神経 / 神経変性 |
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| Outline of Final Research Achievements |
The findings are that 1) no statistical differences between wild-type and NF-H KO mice were found in reproductive parameters, indicating that NF-H expression itself scarcely influence on reproductive system, 2) IDPN showed a transient reproductive toxicity on gonads of both sexes directly and low dose IDPN does not promote oocyte maturation, and 3) neuronal proteins tau and FMR1 were expressed in specific types (including oocyte) of ovarian cells.
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Report
(5 results)
Research Products
(11 results)
