Neurophysiological study for retention and retrieval in episodic memory.

• Project/Area Number: 25460311
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Environmental physiology(including physical medicine and nutritional physiology)
• Research Institution: University of Toyama
• Principal Investigator: Hori Etsuro 富山大学, 大学院医学薬学研究部(医学), 教授 (90313600)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000); Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2014: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000); Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
• Keywords: エピソード記憶 / 空間認知 / 空間移動 / 空間記憶 / 記憶 / 想起 / ニューロン活動 / 霊長類

Outline of Final Research Achievements

Behavioral change was analyzed which depend on establishment of learning on spatial navigation task. After established spatial learning, monkeys might used distal spatial cues to estimate their own location and reward areas. Place-selective neuronal activity was observed from monkey retrosplenial cortex during spatial navigation task. These neuronal activity was reduced by added or removed distal spatial cues, and not responded to novel environment. These results suggest that retrosplenial neuron has a function of memory retention or retrieval about spatial information.

Research Products

• [Journal Article] Place-related neuronal activity in the monkey parahippocampal gyrus and hippocampal formation during virtual navigation. (2014)
  • Author(s): Furuya Y, Matsumoto J, Hori E, Boas CV, Tran AH, Shimada Y, Ono T, Nishijo H.
  • Journal Title: Hippocampus Volume: 24 Issue: 1 Pages: 113-130
  • DOI: 10.1002/hipo.22209
  • Peer Reviewed
• [Presentation] Quantitative analysis of monkey emotional gestures by a markerless 3D motion capture. (2015)
  • Author(s): Rafael V Bretas, Tomoya Nakamura, Jumpei Matsumoto, Yusaku Takamura, Etsuro Hori, Taketoshi Ono, Hisao Nishijo.
  • Organizer: Neuroscience2015
  • Place of Presentation: Chicago, USA.
  • Year and Date: 2015-10-17
  • Int'l Joint Research
• [Presentation] Neural representation of trajectory in the monkey hippocampus (2014)
  • Author(s): Rafael V. Bretas, Etsuro Hori, Jumpei Matsumoto, Taketoshi Ono, Hisao Nishijo
  • Organizer: Vision, Memory Thought: how cognition emerges from neural network
  • Place of Presentation: 東京大学 伊藤国際学術研究センター
  • Year and Date: 2014-12-06 – 2014-12-07
• [Presentation] サル海馬体および海馬傍回における空間依存的報酬関連ニューロン. (2013)
  • Author(s): 松本惇平, 古谷陽一, ラファエル・ブレタス・ビエイラ, 堀 悦郎, 嶋田 豊, 小野武年, 西条寿夫.
  • Organizer: 日本味と匂学会第47回大会
  • Place of Presentation: 仙台市民会館