| Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2014: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2013: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Outline of Final Research Achievements |
Glucagon-like peptide-1 (GLP-1) is one of gut hormones act as a satiety signal in the brain. However, circulating GLP-1 is unlikely to reach receptors in the brain because of its rapid metabolization in the blood. GLP-1 is also produced in a small population of cells in the brainstem. We propose that the GLP-1 releasing neurons play an important role in satiety and have started to characterize the relationship between satiety molecules (e.g. orexin, serotonin, and glucose), and the GLP-1 releasing neurons in the brainstem.
|
