Budget Amount *help |
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥260,000 (Direct Cost: ¥200,000、Indirect Cost: ¥60,000)
Fiscal Year 2014: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2013: ¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
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Outline of Final Research Achievements |
The present study firstly demonstrated that tonsillar follicular dendritic cells of IgA nephropathy patients express thymic stromal lymphopoietin (TSLP) and its receptor, and the TSLP-TSLPR interaction promotes IgA class switching through the cooperative role of transforming growth factor-β1, B cell-activating factor of the tumor necrosis factor family, a proliferation-inducing ligand and activation-induced cytidine deaminase.
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