• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Epidemiologic and pathogenic features of an emerging enteropathogen, Escherichia albertii

Research Project

Project/Area Number 25460539
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Bacteriology (including mycology)
Research InstitutionKagoshima University (2015)
University of Miyazaki (2013-2014)

Principal Investigator

OOKA TADASUKE  鹿児島大学, 医歯学域医学系, 講師 (50363594)

Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsEscherichia albertii / ゲノム / 病原性 / 検出系 / 新興下痢症起因菌 / III型分泌機構 / 比較ゲノム解析 / ゲノム解析 / 保菌宿主
Outline of Final Research Achievements

Escherichia albertii is an emerging enteropathogen. We developed a nested PCR system to detect E. albertii effectively and directly from feces or environmental samples. To understand the host species distribution of E. albertii, we performed screening from human and animal feces with the system. The screening revealed that E. albertii detected in pig and free-range chicken with an high frequency but not in healthy individual. We also determined the draft genome sequences of 26 E. albertii strains isolated from animal and diarrheal patients and performed robust intra-species and intra-genus genomic comparisons. Our analysis identified the core genome of E. albertii, the accessory genome specific to E. albertii, and a possible core genome of the genus Escherichia. Several unique or notable genetic features of E. albertii have also been identified. These data provide insights into the genomic evolution, adaptation, and virulence mechanisms of E. albertii.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (17 results)

All 2016 2015 2014 2013 Other

All Int'l Joint Research (2 results) Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 3 results,  Open Access: 2 results) Presentation (12 results) (of which Invited: 1 results)

  • [Int'l Joint Research] Federal Institute for Risk Assessment(Germany)

    • Related Report
      2015 Annual Research Report
  • [Int'l Joint Research] Universidade Federal de Sao Paulo(Brazil)

    • Related Report
      2015 Annual Research Report
  • [Journal Article] Defining the Genome Features of Escherichia albertii, an Emerging Enteropathogen Closely Related to Escherichia coli2015

    • Author(s)
      Ooka T, Ogura Y, Katsura K, Seto K, Kobayashi H, Kawano K, Tokuoka E, Furukawa M, Harada S, Yoshino S, Seto J, Ikeda T, Yamaguchi K, Murase K, Gotoh Y, Imuta N, Nishi J, Gomes TA, Beutin L, Hayashi T.
    • Journal Title

      Genome Biol Evol

      Volume: 7(12) Pages: 3170-3179

    • DOI

      10.1093/gbe/evv211

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The Shiga toxin 2 production level in enterohemorrhagic Escherichia coli O157:H7 is correlated with the subtypes of toxin-encoding phage.2015

    • Author(s)
      Yoshitoshi Ogura, Shakhinur Islam Mondal, Md Rakibul Islam, Toshihiro Mako, Kokichi Arisawa, Keisuke Katsura, Tadasuke Ooka, Yasuhiro Gotoh, Kazunori Murase, Makoto Ohnishi, and Tetsuya Hayashi
    • Journal Title

      Scientific Reports

      Volume: 5 Issue: 1 Pages: 16663-16663

    • DOI

      10.1038/srep16663

    • NAID

      120006875675

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] Shiga Toxin 2f-Producing Escherichia albertii from a Symptomatic Human2014

    • Author(s)
      Murakami K, Etoh Y, Tanaka E, Ichihara S, Horikawa K, Kawano K, Ooka T, Kawamura Y, Ito K
    • Journal Title

      Japanese Journal of Infectious Diseases

      Volume: 67(3)

    • NAID

      130004757082

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Presentation] 新興下痢症起因菌Escherichia albertiiのO抗原コード領域の多様性2016

    • Author(s)
      大岡唯祐、勢戸和子、小椋義俊、井口純、藺牟田直子、吉家清貴、林哲也、西順一郎
    • Organizer
      第89回日本細菌学会総会
    • Place of Presentation
      大阪国際交流センター(大阪府大阪市)
    • Year and Date
      2016-03-23
    • Related Report
      2015 Annual Research Report
  • [Presentation] Genomic diversity and evolutionary insights of Escherichia albertii, an emerging enteropathogen closely related to Escherichia coli2016

    • Author(s)
      Tadasuke Ooka
    • Organizer
      SMBE Satellite Workshop on Genome Evolution in Pathogen Transmission and Disease
    • Place of Presentation
      志賀レークホテル(長野県下高井郡山ノ内町)
    • Year and Date
      2016-02-22
    • Related Report
      2015 Annual Research Report
  • [Presentation] 志賀毒素サブタイプStx2f転換ファージの構造比較及び種間伝播に関する解析2015

    • Author(s)
      大岡唯祐、勢戸和子、磯部順子、瀬戸順次、池田徹也、 藺牟田直子、西順一郎
    • Organizer
      第85回感染症学会西日本地方会
    • Place of Presentation
      奈良春日野国際フォーラム甍/奈良ホテル(奈良県奈良市)
    • Year and Date
      2015-10-15
    • Related Report
      2015 Annual Research Report
  • [Presentation] EHECおよびE. albertiiにおけるStx2f転換ファージの解析2015

    • Author(s)
      大岡唯祐、勢戸和子、磯部順子、瀬戸順次、池田徹也、 藺牟田直子、小椋義俊、西順一郎、林哲也
    • Organizer
      第19回腸管出血性大腸菌感染症研究会
    • Place of Presentation
      国立医薬品食品衛生研究所(東京都世田谷区)
    • Year and Date
      2015-07-09
    • Related Report
      2015 Annual Research Report
  • [Presentation] 新興下痢原性病原菌Escherichia albertiiのゲノム解析と疫学ツールの開発2015

    • Author(s)
      大岡唯祐、勢戸和子
    • Organizer
      第89回日本感染症学会総会・学術講演会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2015-04-16
    • Related Report
      2015 Annual Research Report
  • [Presentation] 新規下痢原性病原菌Escherichia albertiiのゲノム特性2015

    • Author(s)
      大岡唯祐、勢戸和子、後藤恭宏、小椋義俊、林哲也
    • Organizer
      第88回日本細菌学会総会
    • Place of Presentation
      長良川国際会議場(岐阜県・岐阜市)
    • Year and Date
      2015-03-26 – 2015-03-28
    • Related Report
      2014 Research-status Report
  • [Presentation] 新興病原体 Escherichia albertii のゲノムおよび疫学解析2014

    • Author(s)
      大岡唯祐、勢戸和子、小野英俊、河野喜美子、小林秀樹、吉野修司、瀬戸順次、山口敬治、古川真斗、徳岡英亮、井口純、藺牟田直子、原田誠也、西順一郎、桂啓介、小椋義俊、林哲也
    • Organizer
      第35回日本食品微生物学会学術総会
    • Place of Presentation
      大阪府立大学(大阪府・大阪市)
    • Year and Date
      2014-09-18 – 2014-09-19
    • Related Report
      2014 Research-status Report
  • [Presentation] 人獣共通新興病原体 Escherichia albertii のゲノムの特徴と診断疫学マーカーの開発2014

    • Author(s)
      大岡唯祐、林哲也
    • Organizer
      第157回日本獣医学会学術集会・微生物分科会(ウイルス)シンポジウム
    • Place of Presentation
      北海道大学高等教育推進機構(北海道・札幌市)
    • Year and Date
      2014-09-09 – 2014-09-12
    • Related Report
      2014 Research-status Report
    • Invited
  • [Presentation] 湧き水を原因としたEscherichia albertiiによる食中毒2014

    • Author(s)
      緒方喜久代、大岡唯祐、成松浩志、林哲也
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      タワーホール船堀(東京)
    • Related Report
      2013 Research-status Report
  • [Presentation] 熊本県で発生したEscherichia albertii食中毒2事例について2014

    • Author(s)
      原田誠也、大岡唯祐、林哲也
    • Organizer
      第87回日本細菌学会総会
    • Place of Presentation
      タワーホール船堀(東京)
    • Related Report
      2013 Research-status Report
  • [Presentation] 新興病原体Escherichia albertii のゲノム及びゲノム比較解析2013

    • Author(s)
      大岡唯祐、勢戸和子、河野喜美子、小林秀樹、井口純、瀬戸順次、山口敬治、 古川真斗、徳岡英亮、原田誠也、小野英俊、吉野修司、Lothar Beutin、 西順一郎、伊藤武彦、桂啓介、後藤恭宏、小椋義俊、林哲也
    • Organizer
      第17回腸管出血性大腸菌感染症研究会
    • Place of Presentation
      動物衛生研究所(つくば)
    • Related Report
      2013 Research-status Report
  • [Presentation] 熊本県で発生したEscherichia albertiiによる食中毒事例について2013

    • Author(s)
      古川真斗、福司山郁恵、奥田将之、松尾繁、郷博臣、大岡唯祐、林哲也、原田誠也
    • Organizer
      第34回日本食品微生物学会学術総会
    • Place of Presentation
      タワーホール船堀(東京)
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi