Genomic analysis of Shiga toxin-producing Escherichia coli belonging novel O serogroups
| Project/Area Number |
25460540
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Bacteriology (including mycology)
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| Research Institution | University of Miyazaki |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
IYODA SUNAO 国立感染症研究所, 細菌第一部, 主任研究官 (70300928)
OHNISHI MAKOTO 国立感染症研究所, 細菌第一部, 部長 (10233214)
SETO KAZUKO 大阪府立公衆衛生研究所, 細菌課, 主任研究員 (70211323)
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥5,200,000 (Direct Cost: ¥4,000,000、Indirect Cost: ¥1,200,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2013: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 志賀毒素産生性大腸菌 / O血清群 / PCR / 血清型 / ゲノム解析 / 腸管出血性大腸菌 / ゲノム / 進化系統 |
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| Outline of Final Research Achievements |
We conducted genomic analysis of Shiga toxin-producing Escherichia coli belonging novel O serogroups (O182-O187). Based on the O-antigen biosynthesis gene clusters extracted from draft genomes, each O-serogroup-specific PCR method was designed. Screening by using the PCR methods showed that two O182, six O183, one O185 and one O186 were identified from 2014-2015 STEC isolates in Japan.
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Report
(4 results)
Research Products
(6 results)
