Research Project
Grant-in-Aid for Scientific Research (C)
Plasmalogens (Pls) are glycerophospholipids owning antioxidative effect, so it is conceivable that Pls may prevent arteriosclerosis and Alzheimer's disease. In our study, chemical synthesis method for choline Pls (PlsCho) has been improved; chemical synthesis method for ethanolamine Pls (PlsEtn) has been established.Comprehensively qualitative and quantitative analyses of Pls in human serum have been carried out by LC-MS/MS using the synthetic Pls standards. The concentration ofPlsEtn18:0/20:4shows higher than that of PlsCho18:0/20:4 in human serum. Some mouses were immunized with BSA-plasmalogens obtained from chemical synthesis.
All 2015 2014 2013
All Journal Article (7 results) (of which Peer Reviewed: 7 results, Acknowledgement Compliant: 1 results) Presentation (7 results) (of which Invited: 1 results) Patent(Industrial Property Rights) (1 results)
Clinica Chimica Acta
Volume: 437 Pages: 147-154
10.1016/j.cca.2014.07.024
J Lipid Res
Volume: 55 Issue: 5 Pages: 956-65
10.1194/jlr.p045591
Anal Bioanal Chem
Volume: 405 Issue: 14 Pages: 4981-4987
10.1007/s00216-013-6903-4
J Biomed Nanotechnol
Volume: 9 Pages: 303-6
Annals of Clinical Biochemistry
Volume: 50 Issue: 5 Pages: 450-456
10.1177/0004563213476272
Ann Clin Biochem
Volume: 50 Issue: 5 Pages: 465-72
10.1177/0004563212473446
Volume: 50 Issue: 6 Pages: 564-70
10.1177/0004563213481586