Improvement of choice reaction time and hand tremor measurement for the assessment of motor nervous effects of environmental chemicals

• Project/Area Number: 25460736
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Epidemiology and preventive medicine
• Research Institution: Akita University
• Principal Investigator: Iwata Toyoto 秋田大学, 医学(系)研究科(研究院), 助教 (00321894)
• Co-Investigator(Kenkyū-buntansha): MURATA Katsuyuki 秋田大学, 医学系研究科, 教授 (80157776) ; HORIGUCHI Hyogo 北里大学, 医学部, 教授 (90254002)
• Project Period (FY): 2013-04-01 – 2016-03-31
• Project Status: Completed (Fiscal Year 2015)
• Budget Amount: ¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000); Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000); Fiscal Year 2014: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000); Fiscal Year 2013: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
• Keywords: 手のふるえ / 反応時間 / 呼気一酸化炭素 / 量－影響関係 / 健康影響評価 / 周波数分析 / 選択反応時間 / 喫煙 / 呼気中一酸化炭素 / 単純反応時間 / 周波数解析

Outline of Final Research Achievements

Choice reaction time including Stroop task was applied for the assessment of motor nerveous effects of chemicals. Hand tremor measurement was also improved to include 15～80 Hz range for the analysis. These methods including measurement of postural balance were applied for apparently healthy adult subjects. Dose-effect relationship between exhaled carbon monoxide and enlarged tremor of right hand was observed among them.

Research Products

• [Journal Article] The Association between Dietary Lifestyles and Hepatocellular Injury in Japanese Workers (2013)
  • Author(s): Iwata T, Arai K, Saito N, Murata K
  • Journal Title: The Tohoku Journal of Experimental Medicine Volume: 231 Issue: 4 Pages: 257-263
  • DOI: 10.1620/tjem.231.257
  • NAID: 130004460098
  • ISSN: 0040-8727, 1349-3329
  • Peer Reviewed
• [Presentation] 販売従事者における食行動と肝障害の関係
  • Author(s): 岩田豊人、荒井香織、齋藤憲光、村田勝敬
  • Organizer: 産業衛生学会東北地方会
  • Place of Presentation: 盛岡市
• [Presentation] 魚介類摂取量から推定した長鎖不飽和脂肪酸摂取量と血漿中濃度との関係
  • Author(s): 岩田豊人，村田勝敬
  • Organizer: 秋田県公衆衛生学会
  • Place of Presentation: 秋田市
• [Remarks] 環境保健学講座ホームページ
  • URL: http://www.med.akita-u.ac.jp/~eisei/