| Project/Area Number |
25460751
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Osaka University |
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Principal Investigator |
Yamada Sachiko 大阪大学, 医学部附属病院, 医療技術職員 (40623054)
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| Co-Investigator(Kenkyū-buntansha) |
上口 貴志 国立研究開発法人情報通信研究機構, 脳情報通信融合研究センター脳機能解析研究室, 主任研究員 (80403070)
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| Project Period (FY) |
2013-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2014: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2013: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | CT / 被ばく / 核医学 / dual-energy / 画像再構成 / 画質 / PET / SPECT / 減弱補正 / PET/SPECT / 仮想単色CT / 画質評価 / 放射線医学 / PET/CT / 検診 |
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| Outline of Final Research Achievements |
The radiation dose in PET/CT procedures comes not only from internal exposure by administrated radioactive tracers but also from external exposure by the x-ray irradiation. Although most common PET/CT protocols are based on “low-dose” CT, its radiation dose is still non-negligible because reducing radiation dose is also directly associated with decreasing both image quality and quantitative accuracy on CT images. In this study, we applied novel CT acquisition and reconstruction techniques to further reduce radiation dose in PET/CT. The effects of such techniques on image quality and quantitative accuracy were also investigated.
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