| Project/Area Number |
25460777
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Keio University |
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Principal Investigator |
Ueda Ikuko 慶應義塾大学, 医学部, その他 (80571398)
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| Co-Investigator(Kenkyū-buntansha) |
Kohsaka Shun 慶應義塾大学, 医学部, 特任講師 (30528659)
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| Research Collaborator |
Saito Itsuka
Susa Junko
Sato Hiromi
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| Project Period (FY) |
2013-04-01 – 2016-03-31
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| Project Status |
Completed (Fiscal Year 2015)
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| Budget Amount *help |
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 急性心筋梗塞 / 再灌流療法 / ST上昇型心筋梗塞 / 心筋梗塞 / データベース / クリニカルリサーチコーディネーター |
|---|
| Outline of Final Research Achievements |
We aimed to evaluate the risk of delayed PCI for STEMI in the dataset from JCD-KiCS. We analyzed ① baseline characteristics ②correlation between the delayed STEMI and occurrence of in-hospital cardiogenic shock, and ③ long-term mortality of the delayed STEMI. We studied a total of 625 consecutively enrolled acute MI patients (from July 2009 to March 2013) and divided them into 94 STEMI>12h, 353 STEMI<12h and 178 non-STEMI groups.
Mean patient age was 66.0±11.7 years for STEMI>12h group. STEMI>12h patients were less likely to have other risk factors for coronary artery disease. The occurrence of cardiogenic shock was higher in STEMI>12h compared with the other groups. With multivariate logistic regression modeling, risk of in-hospital cardiogenic shock was equivalent (OR, 1.08; 95% CI:0.45-2.63). The Composite end-point defined reoccurrence of ACS and hospitalization for acute heart failure and major bleeding was equivalent between the two groups (STEMI>12h 13.2%, STEMI<12h 14.3%).
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