• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The search for effective food ingredient in cancer prevention to control epigenetics

Research Project

Project/Area Number 25460781
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Epidemiology and preventive medicine
Research InstitutionChubu University

Principal Investigator

YAMANOSHITA Osamu  中部大学, 生命健康科学部, 講師 (50424924)

Co-Investigator(Kenkyū-buntansha) NASU Tamie  中部大学, 生命健康科学部, 教授 (10020794)
Project Period (FY) 2013-04-01 – 2016-03-31
Project Status Completed (Fiscal Year 2015)
Budget Amount *help
¥5,070,000 (Direct Cost: ¥3,900,000、Indirect Cost: ¥1,170,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2014: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2013: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywordsエピジェネティクス / ガン / 食品 / メチル化
Outline of Final Research Achievements

Modification of DNA are found in the process of malignant transformation from normal cells in many cancers. If this phenomenon in the regulatory site of the tumor suppressor gene occurs, it is believed that malignant transformation is likely to occur. In the present study, the chemical substance of the food component to cause the re-expression and modification of the tumor suppressor gene was to explore, but a new material was not found. Though the benign tumor of a model mouse of the multi-stage carcinogenesis was used, it was not observed these effect.

Report

(4 results)
  • 2015 Annual Research Report   Final Research Report ( PDF )
  • 2014 Research-status Report
  • 2013 Research-status Report
  • Research Products

    (5 results)

All 2015 2014 2013

All Journal Article (3 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (1 results) Book (1 results)

  • [Journal Article] Carcinogenic risk of chromium, copper and arsenic in CCA-treated woods.2015

    • Author(s)
      Ohgami N, Yamanoshita O, Thang ND, Yajima I, Nakano C, Wu W, Ohnuma S, Kato M.
    • Journal Title

      Environ Pollut

      Volume: 206 Pages: 456-460

    • DOI

      10.1016/j.envpol.2015.07.041

    • Related Report
      2015 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] GNG2 inhibits invasion of human malignant melanoma cells with decreased FAK activity.2014

    • Author(s)
      Yajima I, Kumasaka MY, Yamanoshita O, Zou C, Li X, Ohgami N, Kato M
    • Journal Title

      Am J Cancer Res

      Volume: 4 Pages: 182-188

    • Related Report
      2013 Research-status Report
    • Peer Reviewed
  • [Journal Article] Occupational trichloroethylene hypersensitivity syndrome: Human herpesvirus 6 reactivation and rash phenotypes.2013

    • Author(s)
      Michihiro Kamijima, M.D., Ph.D.; Hailan Wang; Osamu Yamanoshita; Yuki Ito; Lihua Xia; Yukie Yanagiba; Cishan Chen; Ai Okamura; Zhenlie Huang; Xinxiang Qiu; Xiangrong Song; Tingfeng Cai; Lili Liu; Yichen Ge; Yingyu Deng; Hisao Naito; Tetsushi Yoshikawa; Mikiko Tohyama; Laiyu Li; Hanlin Huang; Tamie Nakajima
    • Journal Title

      J Dermatol Sci.

      Volume: 72 Pages: 218-224

    • Related Report
      2013 Research-status Report
  • [Presentation] トリクロロエチレンによる重症皮膚肝障害の個体感受性マーカーの解析2015

    • Author(s)
      山ノ下 理、内藤 久雄、伊藤 由起、王 海蘭、黄 漢林、上島 通浩、那須 民江
    • Organizer
      日本産業衛生学会東海地方会
    • Place of Presentation
      名古屋大学医学部(愛知県名古屋市)
    • Year and Date
      2015-05-21
    • Related Report
      2015 Annual Research Report
  • [Book] Hypersensitivity Dermatitis and Hepatitis2014

    • Author(s)
      Kamijima M, Wang H, Yamanoshita O, Ito Y, Nakajima T
    • Publisher
      Humana Press
    • Related Report
      2013 Research-status Report

URL: 

Published: 2014-07-25   Modified: 2019-07-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi